hemorrhagic metalloproteinase

extracted from Vipera berus berus venom; hydrolyzes casein, fibrinogen and splits the insulin B chain at positions Ala(14)-Leu(15), Tyr(16)-Leu(17), His(10)-Leu(11); digests alpha chain of fibrinogen

Networked: 5 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Anai, Keita: 1 article (01/2002)
2.	Maruyama, Masugi: 1 article (01/2002)
3.	Sugiki, Masahiko: 1 article (01/2002)
4.	Yoshida, Etsuo: 1 article (01/2002)
5.	Franceschi, A: 1 article (01/2000)
6.	Gutiérrez, J M: 1 article (01/2000)
7.	Mora, N: 1 article (01/2000)
8.	Rucavado, A: 1 article (01/2000)

Related Diseases

1.	Snake Bites (Snake Bite) 01/01/2002 - "The present study was undertaken to examine the effect of a hemorrhagic metalloproteinase in Bothrops jararaca venom, jararafibrase I (JF I), on the development of coagulopathy using rat snakebite model. "
2.	Hemorrhage 01/01/2000 - "BaH4 is a hemorrhagic metalloproteinase which may play a relevant role in local and systemic bleeding characteristic of B. " 08/01/1998 - "Jararafibrase I is a hemorrhagic metalloproteinase purified from Bothrops jararaca venom, which induces local hemorrhage by degrading the basement membrane components. "
3.	Experimental Sarcoma 05/01/1990 - "Type IV collagen, solubilized from Engelbreth-Holm-Swarm (EHS) tumor basement membranes is digested by a hemorrhagic metalloproteinase, Ht-e, isolated from the crude venom of the Western Diamondback rattlesnake, Crotalus atrox. "
4.	Necrosis 02/01/1995 - "Skeletal muscle necrosis and regeneration after injection of BaH1, a hemorrhagic metalloproteinase isolated from the venom of the snake Bothrops asper (Terciopelo)."

Related Drugs and Biologics

1.	Bothrops jararaca Venom
2.	jararafibrase I
3.	Venoms
4.	Collagen Type IV (Type IV Collagen)