alpha helical corticotropin-releasing hormone

see also alpha-helical CRF(9-41); a corticotropin-releasing hormone antagonist

Also Known As:

alpha-helical CRH

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Hormones, Hormone Substitutes, and Hormone Antagonists
- Hormones: 80400
  - Peptide Hormones: 1347
    - Hypothalamic Hormones: 68
      - Pituitary Hormone-Releasing Hormones: 39
        Corticotropin-Releasing Hormone: 2046
        alpha helical corticotropin-releasing hormone: 6
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Nerve Tissue Proteins: 2
    - Neuropeptides: 6772
      - Hypothalamic Hormones: 68
        Pituitary Hormone-Releasing Hormones: 39
        Corticotropin-Releasing Hormone: 2046
        alpha helical corticotropin-releasing hormone: 6
- Peptides: 82426
  - Neuropeptides: 6772
    - Hypothalamic Hormones: 68
      - Pituitary Hormone-Releasing Hormones: 39
        Corticotropin-Releasing Hormone: 2046
        alpha helical corticotropin-releasing hormone: 6
  - Peptide Hormones: 1347
    - Hypothalamic Hormones: 68
      - Pituitary Hormone-Releasing Hormones: 39
        Corticotropin-Releasing Hormone: 2046
        alpha helical corticotropin-releasing hormone: 6

Experts

1.	Barros, D: 2 articles (08/2005 - 04/2004)
2.	Carvalho, F: 2 articles (08/2005 - 04/2004)
3.	Fregoneze, J: 2 articles (08/2005 - 04/2004)
4.	Rezende, E: 2 articles (08/2005 - 04/2004)
5.	Silva, J: 2 articles (08/2005 - 04/2004)
6.	Soares, M: 2 articles (08/2005 - 04/2004)
7.	Fujiwara, K: 1 article (09/2010)
8.	Maejima, Y: 1 article (09/2010)
9.	Maekawa, F: 1 article (09/2010)
10.	Nakagawa, T: 1 article (09/2010)

Related Diseases

1.	Hyperglycemia 08/01/2005 - "Pretreatment with alpha-helical CRH, a CRH antagonist, significantly attenuated quipazine-induced hyperglycemia. " 04/01/2004 - "Pretreatment with alpha-helical CRH, a selective CRH antagonist, significantly blunted fluoxetine-induced hyperglycemia. "
2.	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 06/01/2007 - "Effect of alpha-helical CRH on quantitative electroencephalogram in patients with irritable bowel syndrome."
3.	Sleep Deprivation 12/01/1998 - "Involvement of stress in the sleep rebound mechanism induced by sleep deprivation in the rat: use of alpha-helical CRH (9-41)." 12/01/1998 - "Rats were subjected for 10 h to the classical water-tank sleep-deprivation technique and were given, every 2 h throughout the sleep deprivation period, intracerebroventricular injections of either 100 microg/5 microl of alpha-helical CRH (9-41) or vehicle alone. "
4.	Body Weight (Weight, Body) 09/01/2010 - "These effects of BDNF on food intake and body weight were counteracted by the co-administration of alpha-helical-CRH, an antagonist for the CRH and urocortin receptors CRH-R1/R2, and partly attenuated by a selective antagonist for CRH-R2 but not CRH-R1. "
5.	Atrophy 06/01/1993 - "Subcutaneous infusion for one week with alpha-helical-CRH or corticotropin-inhibiting peptide (1 nmol.min-1), which are competitive inhibitors of CRH and ACTH, evoked a further significant lowering of plasma corticosterone concentration and markedly enhanced adrenal atrophy in hypophysectomized rats. "

Related Drugs and Biologics

1.	Urocortins
2.	Brain-Derived Neurotrophic Factor (BDNF)
3.	Corticotropin-Releasing Hormone Receptors (Corticotropin Releasing-Hormone Receptor)
4.	Quipazine
5.	Fluoxetine (Prozac)
6.	Corticosterone
7.	Adrenocorticotropic Hormone (ACTH)
8.	CRF receptor type 2
9.	ACTH (7-38)

Related Therapies and Procedures

1.	Subcutaneous Infusions
2.	Injections