Hepatitis C virus nucleocapsid protein

antibodies against the above protein are found in patients with hepatocellular carcinoma; amino acid sequence has been determined; encodes a weakly oncogenic protein

Also Known As:

Networked: 12 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Chen, Ru-Fu: 3 articles (01/2007 - 02/2005)
2.	Li, Zhi-Hua: 3 articles (01/2007 - 02/2005)
3.	Kong, Xian-He: 2 articles (01/2007 - 02/2005)
4.	Chen, Ji-Sheng: 2 articles (02/2005 - 02/2005)
5.	Zou, Sheng-Quan: 2 articles (02/2005 - 02/2005)
6.	Dansako, Hiromichi: 1 article (08/2014)
7.	Hiramoto, Hiroki: 1 article (08/2014)
8.	Ikeda, Masanori: 1 article (08/2014)
9.	Kato, Nobuyuki: 1 article (08/2014)
10.	Wakita, Takaji: 1 article (08/2014)

Related Diseases

1.	Klatskin Tumor 01/01/2007 - "High level expression of hepatitis C virus core protein (HCV-C) was detected in hilar cholangiocarcinoma tissues in our previous studies. " 02/01/2005 - "HCV core protein (HCV C protein) was detected by peroxidase-antiperoxidase assay in surgical specimens from 48 patients with hilar cholangiocarcinoma. "
2.	Neoplasms (Cancer) 02/01/2005 - "To study the effect of hepatitis C virus core protein (HCV-C) on human normal biliary epithelial cells (BEC) transformation and tumor development. " 11/01/2001 - "Here we have examined the effects of ethanol on hepatitis B protein X (HBX)- or hepatitis C core protein (HCV core protein)-mediated activation of NF-kappaB, a critical signal in hepatic injury, regeneration, and tumor transformation. "
3.	Chronic Hepatitis C 05/01/2005 - "We investigated whether serial determination of IgM to HCV core protein (HCV IgM) may be useful to identify acute hepatitis C (AHC) and to distinguish this disease from reactivation of chronic hepatitis C (r-CHC). " 04/01/2003 - "To verify whether serial determination of titre of IgM to HCV core protein (HCV IgM) may be useful to distinguish acute hepatitis C (AHC) from reactivation of chronic hepatitis C (r-CHC), we studied 18 consecutive patients with AHC (identified by seroconversion to anti-HCV) and 15 consecutive patients who had been anti-HCV positive for at least one year at the time of reactivation. " 01/01/1999 - "Furthermore, many patients with chronic hepatitis C virus infection have reactivity to an autoantigen of unknown significance known as GOR that has protein sequence homology with both hepatitis C virus nucleocapsid protein as well as HTLV-1 gag. " 09/01/1993 - "Four monospecific antibodies against the hepatitis C virus nucleocapsid protein, which was expressed by recombinant baculovirus, were obtained by Epstein-Barr virus transformation of B cells from three patients with chronic hepatitis C virus infection. "
4.	Hepatitis C 05/01/2005 - "We investigated whether serial determination of IgM to HCV core protein (HCV IgM) may be useful to identify acute hepatitis C (AHC) and to distinguish this disease from reactivation of chronic hepatitis C (r-CHC). " 04/01/2003 - "To verify whether serial determination of titre of IgM to HCV core protein (HCV IgM) may be useful to distinguish acute hepatitis C (AHC) from reactivation of chronic hepatitis C (r-CHC), we studied 18 consecutive patients with AHC (identified by seroconversion to anti-HCV) and 15 consecutive patients who had been anti-HCV positive for at least one year at the time of reactivation. " 11/01/2001 - "Here we have examined the effects of ethanol on hepatitis B protein X (HBX)- or hepatitis C core protein (HCV core protein)-mediated activation of NF-kappaB, a critical signal in hepatic injury, regeneration, and tumor transformation. "
5.	Virus Diseases (Viral Diseases) 01/01/1999 - "Furthermore, many patients with chronic hepatitis C virus infection have reactivity to an autoantigen of unknown significance known as GOR that has protein sequence homology with both hepatitis C virus nucleocapsid protein as well as HTLV-1 gag. " 09/01/1993 - "Four monospecific antibodies against the hepatitis C virus nucleocapsid protein, which was expressed by recombinant baculovirus, were obtained by Epstein-Barr virus transformation of B cells from three patients with chronic hepatitis C virus infection. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Immunoglobulin M (IgM)
3.	Hepatitis C Antibodies
4.	NF-kappa B (NF-kB)
5.	RNA (Ribonucleic Acid)
6.	RNA-Directed DNA Polymerase (Reverse Transcriptase)
7.	Peroxidase (Myeloperoxidase)
8.	Enzymes
9.	Autoantigens
10.	Antigen-Antibody Complex (Immune Complex)