apolipoprotein E4 (Philadelphia)
a variant of apolipoprotein E4, with glutamic acid at 13 replaced by lysine and arginine at 145 replaced by cysteine (Glu13Lys, Arg145Cys); associated with severe type III hyperlipoproteinemia
Also Known As:
apo E-4 Philadelphia; apoE4 Philadelphia; apolipoprotein E-4 Philadelphia
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Bio-Agent Context: Research Results