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protamine 2

RefSeq NM_002762
Also Known As:
HPI1 protein, human; HPI2 protein, human; HPS1 nuclear protein, human; HPS2 nuclear protein, human; PRM2 protein, human; PROTA2 protein, rat; Prm2 protein, mouse; Prm2 protein, rat; basic nuclear protein HPS1, human; basic nuclear protein HPS2, human; nuclear basic protein HPI1, human; nuclear basic protein HPI2, human; nuclear protein HPS1, human; nuclear protein HPS2, human; protamine 2 protein, human; protamine 2, mouse; protamine 2, rat
Networked: 22 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Carrell, Douglas T: 3 articles (06/2011 - 05/2005)
2. Aoki, Vincent W: 2 articles (09/2007 - 05/2005)
3. Arévalo, Lena: 1 article (01/2022)
4. Bedford, Erin: 1 article (01/2022)
5. Flannigan, Ryan: 1 article (01/2022)
6. Merges, Gina Esther: 1 article (01/2022)
7. Neumann, Isabelle Sophie: 1 article (01/2022)
8. Oben, Franka Enow: 1 article (01/2022)
9. Robinson, Meghan: 1 article (01/2022)
10. Schneider, Simon: 1 article (01/2022)

Related Diseases

1. Azoospermia
09/01/2017 - "Furthermore, we also found that OCTN2 overexpression dramatically increased the levels of biomarkers associated with spermatogenesis, including azoospermia-like (DAZL), phosphoglycerate kinase 2 (PGK2), and protamine 2 (PRM2). "
01/01/2022 - "Reverse transcription qualitative polymerase chain reaction analysis showed that after 12 days in spermatogenic media, the bioprints substantially up-regulated spermatogenic gene expression on par with nonbioprinted controls and showed a particularly significant improvement in genes involved in spermatogonial stem cell maintenance: inhibitor of deoxyribonucleic acid binding 4 by 365-fold; fibroblast growth factor 3 by 94,152-fold; stem cell growth factor receptor KIT by twofold; stimulated by retinoic acid 8 by 125-fold; deleted in azoospermia-like by 114-fold; synaptonemal complex protein 3 by sevenfold; zona pellucida binding protein by twofold; transition protein 1 by 2,908-fold; and protamine 2 by 11-fold. "
04/01/2017 - "Quantitative polymerase chain reaction analysis revealed that 20%-40% CCM induced the highest expression of primordial germ cell-specific (deleted in Azoospermia- like (Dazl), dead (Asp-Glu-Ala-Asp) box polypeptide 4 (Vasa also known as DDX4) and promyelocytic leukemia zinc finger protein (Plzf)); meiotic (synaptonemal complex protein 3 (Sycp3), mutl homolog I (Mlh1), transition protein 1/2 (Tnp1/2) and protamine 2 (Prm2); spermatocyte-specific boule-like RNA binding protein (Boule) and tektin 1 (Tekt1)) and oocyte-specific growth differentiation factor 9 (Gdf9) and zona pellucida 2 /3 (Zp2/3)) genes over 8-14 days in culture. "
2. Male Infertility (Male Sterility)
3. Oligospermia (Oligozoospermia)
4. B-Cell Lymphoma (Lymphoma, B Cell)
5. Infertility (Sterility)

Related Drugs and Biologics

1. Proteins (Proteins, Gene)
2. spermatid transition proteins
3. Fibroblast Growth Factor 3
4. Growth Factor Receptors
5. Tretinoin (Retinoic Acid)
6. DNA (Deoxyribonucleic Acid)
7. Carrier Proteins (Binding Protein)
8. Protamines (Protamine Sulfate)
9. Histones (Histone)
10. Growth Differentiation Factor 9