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dimethylpropiothetin (dimethylsulfoniopropionate)

has antineoplastic activity; RN given refers to hydroxide inner salt
Also Known As:
dimethylsulfoniopropionate; (2-carboxyethyl)dimethylsulfonium chloride; 3-dimethylsulfoniopropionate; DMPT; S,S-dimethyl-beta-propiothetin; S-dimethylsulfonium propionic acid; beta-DMSP; beta-dimethylsulfoniopropionate; dimethyl-beta-propiothetin; dimethyl-beta-propiothetin chloride; dimethyl-propiothetin; dimethylpropiothetin chloride; dimethylpropiothetin hydrochloride; dimethylsulfoniopropionate chloride; sulfonium, (2-carboxyethyl)dimethyl-, chloride (1:1); Sulfonium, (2-carboxyethyl)dimethyl-, hydroxide, inner salt
Networked: 29 relevant articles (1 outcomes, 7 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Nakajima, Kenji: 8 articles (03/2015 - 02/2006)
2. Feng, Lin: 3 articles (12/2020 - 03/2020)
3. Jiang, Wei-Dan: 3 articles (12/2020 - 03/2020)
4. Kuang, Sheng-Yao: 3 articles (12/2020 - 03/2020)
5. Liu, Xing-Wei: 3 articles (12/2020 - 03/2020)
6. Liu, Yang: 3 articles (12/2020 - 03/2020)
7. Shi, He-Qun: 3 articles (12/2020 - 03/2020)
8. Tang, Ling: 3 articles (12/2020 - 03/2020)
9. Wu, Pei: 3 articles (12/2020 - 03/2020)
10. Zhou, Xiao-Qiu: 3 articles (12/2020 - 03/2020)

Related Diseases

1. Infections
2. Neoplasms (Cancer)
01/01/1992 - "To better understand this discrepancy in organotropism of the teratogenic and transplacental carcinogenic processes, the present study was undertaken to characterize the neoplasms induced in rat fetuses exposed to DMPT in utero. "
11/01/2023 - "Proliferation and differentiation of MC3T3-E1 cells on PMMA-type cements containing Fe3O4 and TiO2 with increased BPO and DMPT contents need to be investigated in the future; however, our findings will be useful for designing PMMA cements for the hyperthermic treatment of metastatic bone tumors."
01/01/1992 - "Exposure to single intraperitoneal doses of DMPT on gestation day 20 did not produce a classic dose-response pattern: Minimal effects were observed with 10 mg DMPT/kg (occasional renal mesenchymal tumors and brain neoplasms), marked effects were observed with 30 mg DMPT/kg (lower incidence rate of most of the alterations observed with 1 mg/kg on gestation days 16, 18, and 20), and no effects were observed with 60 mg DMPT/kg. DMPT administered intraperitoneally at 1 mg/kg body weight on gestation days 16, 18, and 20 is an animal model of transplacental chemically induced renal neoplasms, which provide lesions with similarities to both intralobar nephrogenic rests and congenital mesoblastic nephroma of humans. "
01/01/2016 - "N, N-dimethyl-p-toluidine (DMPT; Cas No. 99-97-8), an accelerant for methyl methacrylate monomers in medical devices, is a nasal cavity carcinogen according to a 2-yr cancer study of male and female F344/N rats, with the nasal tumors arising from the transitional cell epithelium. "
3. Hyperhomocysteinemia
4. Parkinson Disease (Parkinson's Disease)
5. Fatigue

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6. Carcinogens
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10. Sulfur