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poly(3- hydroxybutyrate- co- 4- hydroxybutyrate)

biosynthesized in Alcaligenes eutrophus; structure given in first source

Also Known As:

3HB-4-HB; P(3HB-co-4HB); P34HB copolymer

Networked: 7 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Macromolecular Substances: 97
- Polymers: 13051
  - Polyesters: 921
    - Polyhydroxyalkanoates: 56
      - Polyhydroxybutyrates
        poly(3-hydroxybutyrate-co-4-hydroxybutyrate): 7
  - Biopolymers: 773
    - Polyhydroxyalkanoates: 56
      - Polyhydroxybutyrates
        poly(3-hydroxybutyrate-co-4-hydroxybutyrate): 7
Lipids: 114793
- Polyhydroxyalkanoates: 56
  - Polyhydroxybutyrates
    - poly(3-hydroxybutyrate-co-4-hydroxybutyrate): 7

Experts

1.	Bhatia, Shashi Kant: 1 article (12/2021)
2.	Cho, Jang Yeon: 1 article (12/2021)
3.	Gurav, Ranjit: 1 article (12/2021)
4.	Kim, Su Hyun: 1 article (12/2021)
5.	Park, Kyungmoon: 1 article (12/2021)
6.	Park, See-Hyoung: 1 article (12/2021)
7.	Park, Sol Lee: 1 article (12/2021)
8.	Yang, Yung-Hun: 1 article (12/2021)
9.	Isa, Anis Syaffini Mat: 1 article (06/2018)
10.	Leong, Yin-Hui: 1 article (06/2018)

Related Diseases

1.	Body Weight (Weight, Body) 06/01/2018 - "The estimated lethal dose (LD50) of P(3HB-co-4HB) nanoparticles was >2000 mg/kg. No mortality, unusual changes in behaviour, adverse clinical signs, abnormal changes in body weights or food consumption were observed on all animals treated with P(3HB-co-4HB) nanoparticles during 14 days of the acute toxicity study. "
2.	Weight Loss (Weight Reduction) 12/04/2021 - "In addition, this strain showed biodegradability on pellets of poly(3-hydroxybutyrate-co-4-hydroxybutyrate), as confirmed by weight loss and physical property changes. " 08/01/1992 - "Enzymatic degradation processes of microbial copolyesters, poly(3-hydroxybutyrate-co-3-hydroxyvalerate): P(3HB-co-3HV) and poly(3-hydroxybutyrate-co-4-hydroxybutyrate): P(3HB-co-4HB), were studied by the weight loss (erosion) of copolyester films. " 08/01/1993 - "The enzymatic degradation of microbial copolyesters was studied by the weight loss (erosion) of solution-cast films of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) and poly(3-hydroxybutyrate-co-4-hydroxybutyrate). "
3.	Wounds and Injuries (Trauma) 01/11/2023 - "Herein, an instructive poly(3-hydroxybutyrate-co-4-hydroxybutyrate) (P34HB) fibrous wound dressing that integrates an antibacterial ciprofloxacin (CIP) and pro-angiogenic dimethyloxalylglycine (DMOG) is successfully prepared via electrospinning. " 10/06/2016 - "Biomacromolecule immobilization: grafting of fish-scale collagen peptides onto aminolyzed P(3HB-co-4HB) scaffolds as a potential wound dressing."
4.	Myocardial Infarction 06/01/2013 - "P(3HB-co-4HB) has the potential for development as a clinical alternative to current treatment methods for the regeneration of cardiomyocytes in patients with myocardial infarction."

Related Drugs and Biologics

1.	3-Hydroxybutyric Acid (beta-Hydroxybutyric Acid)
2.	Solutions
3.	Peptides (Polypeptides)
4.	Collagen
5.	Ciprofloxacin (Cipro)
6.	poly(3- hydroxybutyrate)- co- (3- hydroxyvalerate)
7.	oxalylglycine