lactosylceramide 1,3- N- acetyl- beta- D- glucosaminyltransferase

Also Known As:

LA2 synthase; Lc3Cer synthetase; UDP-GlcNAc lactosylceramide beta-1,3-N-acetylglucosaminyltransferase; UDPGlcNAc-lactosylceramide beta 1-3N-acetylglucosaminyltransferase; beta3Gn-T5; galactosyl-glucosylceramide N-acetylglucosaminyltransferase; lactosylceramide N-acetylglucosaminyltransferase

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Glycosyltransferases: 784
      - N-Acetylhexosaminyltransferases
        N-Acetylglucosaminyltransferases: 23
        lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase: 2

Experts

1.	Ando, Reiko: 1 article (08/2011)
2.	Fan, Xiaoyan: 1 article (08/2011)
3.	Furukawa, Keiko: 1 article (08/2011)
4.	Furukawa, Koichi: 1 article (08/2011)
5.	Kikkawa, Koji: 1 article (08/2011)
6.	Kondo, Yuji: 1 article (08/2011)
7.	Narimatsu, Hisashi: 1 article (08/2011)
8.	Ohmi, Yuhsuke: 1 article (08/2011)
9.	Okajima, Tetsuya: 1 article (08/2011)
10.	Shibata, Kiyosumi: 1 article (08/2011)

Related Diseases

1.	Glioma (Gliomas) 01/01/2010 - "In this study, we immunized beta3Gn-T5 knockout mice with 3'-isoLM1/3',6'-isoLD1 and produced the anti-3'-isoLM1/3',6'-isoLD1 mAb GMab-1, of the IgG(3) subclass, which should be useful for functional analysis of lacto-series gangliosides and for antibody-based therapy of gliomas."
2.	Neoplasms (Cancer) 08/01/2011 - "These results suggested that beta3Gn-T5 mutant mice are useful for the generation of anti-glycolipid antigens with lacto-/neolacto-core structures expressed in cancer cells."

Related Drugs and Biologics

1.	Immunoglobulin G (IgG)
2.	Gangliosides
3.	Glycolipids
4.	Antigens

Related Therapies and Procedures

1.	Therapeutics