|1.||Rycroft, Beth K: 1 article (01/2008)|
|2.||Christie, Macdonald J: 1 article (01/2008)|
|3.||Vikman, Kristina S: 1 article (01/2008)|
|4.||Corona, Juan Carlos: 1 article (04/2007)|
|5.||Tapia, Ricardo: 1 article (04/2007)|
|6.||Bennett, Michael V L: 1 article (08/2005)|
|7.||Zukin, R Suzanne: 1 article (08/2005)|
|8.||Mashiko, Toshihiro: 1 article (08/2005)|
|9.||Castillo, Pablo E: 1 article (08/2005)|
|10.||Yokota, Hidenori: 1 article (08/2005)|
01/08/1996 - "1-NA-Spm (10, 20 and 40 micrograms/rat) dose-dependently improved kindled seizures and shortened the afterdischarge duration 30 min after the administration. "
01/08/1996 - "The anticonvulsant effect of 1-naphthylacetyl spermine (1-NA-Spm), an analogue of Joro spider toxin, against amygdaloid kindled seizures was studied in rats. "
01/08/1996 - "Potent and long-lasting anticonvulsant effects of 1-naphthylacetyl spermine, an analogue of Joro spider toxin, against amygdaloid kindled seizures in rats."
01/08/1996 - "The present findings demonstrate that 1-NA-Spm acts as a potent and long-acting anticonvulsant against amygdaloid kindled seizures, and also suggest, together with the previous findings, that the calcium-permeable AMPA receptors, which are selectively antagonized by 1-NA-Spm, play a critical role in the seizure generation mechanism of amygdaloid kindling."
05/22/1992 - "The anticonvulsant effect of 1-naphthylacetyl spermine, an analogue of Joro spider toxin (JSTX), was studied against seizures induced by quisqualate (QUIS), a non-NMDA agonist, as assessed electrophysiologically and behaviorally in freely moving rats. "
04/01/2007 - "Perfusion of 1-naphthyl acetyl spermine, a selective blocker of the Ca(2+)-permeable AMPA receptors, and of the intracellular Ca(2+) chelator 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid tetrakis (acetoxymethyl ester) (BAPTA-AM), prevented the AMPA-induced paralysis and reduced by about 50% the loss of motoneurons. "
01/15/2008 - "A significant shortening of the quantal AMPA current decay, a greater inward rectification of the AMPAR-mediated eEPSC amplitude and an increased sensitivity to the Ca2+-permeable AMPAR channel blocker 1-naphthylacetyl spermine (NAS) was also observed, indicating an increase in the contribution of Ca2+-permeable AMPARs at this synapse during inflammation. "
|1.||alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)
|2.||AMPA Receptors (AMPA Receptor)
|3.||JSTX spider toxin
|7.||1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester
|8.||1,2- bis(2- aminophenoxy)ethane- N,N,N',N'- tetraacetic acid (BAPTA)