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erythroagglutinating phytohemagglutinin

a lectin extracted from red kidney beans
Also Known As:
E-PHA; PHA-E
Networked: 55 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Kuo, Wei-Ting: 2 articles (04/2016 - 03/2011)
2. Lin, Feng-Huei: 2 articles (04/2016 - 03/2011)
3. Blennow, Kaj: 1 article (01/2020)
4. Cao, Lin: 1 article (01/2020)
5. Chen, Mingwei: 1 article (01/2020)
6. Chen, Qiushi: 1 article (01/2020)
7. Cheng, Lanming: 1 article (01/2020)
8. Dell, Anne: 1 article (01/2020)
9. Gaunitz, Stefan: 1 article (01/2020)
10. Guan, Feng: 1 article (01/2020)

Related Diseases

1. Neoplasm Metastasis (Metastasis)
09/12/1995 - "In these transfectants, the affinity to leukoagglutinating phytohemagglutinin was reduced, whereas the binding to erythroagglutinating phytohemagglutinin was increased, indicating that the level of beta 1-6 structure was decreased due to competition for substrate between intrinsic GnT-V and ectopically expressed GnT-III. Lung metastasis after intravenous injection of the transfectants into syngeneic and nude mice was significantly suppressed, suggesting that the decrease in beta 1-6 structure suppressed metastasis via a mechanism independent of the murine system. "
01/01/2019 - "In this study, we used a microarray with 55 lectins to screen for altered glycosylation between two metastatic pancreatic cancer lines (Capan-1 and Su.86.86) and two nonmetastatic pancreatic cancer lines (Panc-1 and MIA PaCa-2), and we further analyzed three lectins with high-binding activities (AAL, UEA-I, and PHA-E) in cell motility assays using these pancreatic cancer cells to detect whether blocking certain forms of cell surface glycosylation affects any processes associated with metastasis. "
05/01/1985 - "Using a modified method of Con A, LCH or PHA-E affinity crossed-line immunoelectrophoresis, we studied AFP subfractions in 78 sera including 58 from patients with primary hepatoma, 11 from patients with hepatic metastasis of gastric cancer and 9 from patients with germ cell tumors of the gonads (yolk sac tumor, immature solid teratoma or mature solid teratoma). "
01/01/1986 - "Using a modified method of concanavalin A (Con A), lentil lectin (LCH) or phytohemagglutinin-E (PHA-E) affinity crossed-line immunoelectrophoresis (ACIE), we studied alpha-fetoprotein (AFP) subfractions in 69 sera, including 58 from patients with primary liver cancer and 11 from patients with hepatic metastasis of gastric cancer. "
2. Pancreatic Neoplasms (Pancreatic Cancer)
3. Hepatocellular Carcinoma (Hepatoma)
4. Neoplasms (Cancer)
5. Endodermal Sinus Tumor (Endodermal Sinus Tumors)
05/01/1985 - "Using a modified method of Con A, LCH or PHA-E affinity crossed-line immunoelectrophoresis, we studied AFP subfractions in 78 sera including 58 from patients with primary hepatoma, 11 from patients with hepatic metastasis of gastric cancer and 9 from patients with germ cell tumors of the gonads (yolk sac tumor, immature solid teratoma or mature solid teratoma). "
02/01/1998 - "Affinity electrophoresis of human alpha-fetoprotein (AFP) in amniotic fluid from pregnant women between 6 to 42 weeks of gestation and in the serum of a yolk sac tumor was performed with concanavalin A (Con A), lentil lectin (LCA), erythroagglutinating phytohemagglutinin (E-PHA) and Allomyrina dichotoma lectin (allo A). "
08/01/1990 - "Compared with chronic hepatitis and liver cirrhosis, hepatocellular carcinoma was characterized by the increase in proportions of lentil lectin A-reactive alpha-fetoprotein-L3 and erythroagglutinating phytohemagglutinin-reactive alpha-fetoprotein-P4; the yolk sac tumor was characterized by the increase of concanavalin A-nonreactive alpha-fetoprotein-C1, lentil lectin-A-weakly reactive alpha-fetoprotein-L2, erythroagglutinating phytohemagglutinin-strongly reactive alpha-fetoprotein-P5, and Allomyrina dichotoma lectin-nonreactive, slow-migrating alpha-fetoprotein-Als; and gastrointestinal tumors were characterized by alpha-fetoprotein-C1, alpha-fetoprotein-L2, alpha-fetoprotein-L3, alpha-fetoprotein-P5 and Allomyrina dichotoma-nonreactive alpha-fetoprotein-A1. "

Related Drugs and Biologics

1. Lectins
2. erythroagglutinating phytohemagglutinin
3. lentil lectin
4. alpha-Fetoproteins (alpha-Fetoprotein)
5. Glycoproteins (Glycoprotein)
6. Concanavalin A
7. plants leukoagglutinins
8. Phytohemagglutinins
9. Oligosaccharides
10. Sepharose (Agarose)

Related Therapies and Procedures

1. Intravenous Injections