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ONO 8809

structure given in first source

Also Known As:

ONO-8809; n-decyl (3-(4-bromobenzenesulfonylaminomethyl)bicyclo(2.2.1)hept-2-yl)-5-hexanoate

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Bridged-Ring Compounds: 1
      - Bridged Bicyclo Compounds
        ONO 8809: 4
Polycyclic Compounds: 6
- Bridged-Ring Compounds: 1
  - Bridged Bicyclo Compounds
    - ONO 8809: 4
Lipids: 114793
- Fatty Acids: 27405
  - Unsaturated Fatty Acids: 8236
    - Monounsaturated Fatty Acids: 676
      - ONO 8809: 4

Experts

1.	Higashino, Hideaki: 2 articles (10/2021 - 04/2007)
2.	Nagatani, Yusuke: 2 articles (10/2021 - 04/2007)
3.	Higashino, Toshihide: 1 article (10/2021)
4.	Kinoshita, Kosho: 1 article (10/2021)
5.	Ishizuka, Toshiaki: 1 article (04/2007)
6.	Niwa, Atsuko: 1 article (04/2007)
7.	Ooshima, Kana: 1 article (04/2007)
8.	Tabuchi, Masaki: 1 article (04/2007)

Related Diseases

1.	Stroke (Strokes) 04/01/2007 - "Macrophage accumulation and matrix metalloproteinase-9 (MMP-9) activity in the stroke-negative area in the contralateral cerebral cortex to the stroke lesion of salt-loaded SHRSP and 8-iso-PGF2alpha-treated SHRSP were significantly reduced by ONO-8809 treatment. " 10/01/2021 - "In this study, we focused on evaluating the histological and gene expression effects in the kidneys of stroke-prone spontaneously hypertensive rats (SHRSP) with a high salt intake and the thromboxane A2 / prostaglandin H2 receptor (TPR) blocker ONO-8809. "
2.	Respiratory Hypersensitivity 07/01/1994 - "Thromboxane A2 (TXA2) receptor antagonists ONO-NT-126 and ONO-8809 inhibited the 13,14-dihydro-15-keto-PGF2 alpha-induced airway hyperresponsiveness to histamine, suggesting that the effect of 13,14-dihydro-15-keto-PGF2 alpha on bronchial hyperresponsiveness is likely to be mediated through TXA2." 10/01/1993 - "Thromboxane A2 receptor antagonists ONO-NT-126 and ONO-8809 inhibited the LTC4-induced airway hyperresponsiveness to histamine in a dose-dependent manner, but not the airway wall thickening induced by LTC4, suggesting that the effect of LTC4 on bronchial hyperresponsiveness is likely to be mediated through TXA2."

Related Drugs and Biologics

1.	Prostaglandin H2 Thromboxane A2 Receptors
2.	Thromboxane A2 (A2, Thromboxane)
3.	Salts
4.	Histamine (Histamine Dihydrochloride)
5.	ONO-NT 126
6.	Matrix Metalloproteinase 9 (Gelatinase B)
7.	Leukotriene C4