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3,5-diisopropylsalicylic acid (DIPS)

structure given in first source; RN given refers to parent cpd
Also Known As:
DIPS; 3,5-diisoprophylsalicylate; 3,5-diisopropylsalicylic acid, sodium salt
Networked: 196 relevant articles (16 outcomes, 16 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Fox, L K: 3 articles (02/2015 - 01/2002)
2. Petersen, Bryan D: 3 articles (12/2008 - 03/2005)
3. Sorenson, John R J: 3 articles (11/2004 - 01/2004)
4. Dansky, Tanya: 2 articles (06/2014 - 01/2013)
5. Bush, Ruth: 2 articles (06/2014 - 01/2013)
6. Tompane, Trevor: 2 articles (06/2014 - 01/2013)
7. Huang, Jeannie S: 2 articles (06/2014 - 01/2013)
8. Schimek, Martina: 2 articles (11/2010 - 08/2009)
9. Briegel, Wolfgang: 2 articles (11/2010 - 08/2009)
10. Kamp-Becker, Inge: 2 articles (11/2010 - 08/2009)

Related Diseases

1. Mastitis
2. Infection
3. Asthma (Bronchial Asthma)
4. Seizures (Seizure)
01/01/1999 - "A decrease in NO synthesis in animal models of seizure and radiation injury may account for the anticonvulsant, radioprotectant, and radiorecovery activities of Mn(3)(3,5-DIPS)(6) and Cu(II)(2)(3,5-DIPS)(4)."
03/01/2002 - "It was pointed out that the Cu(2)(DIPS)(4)L(2) complexes (L=diethylether, N,N-dimethylformamide) exhibited no rotorod toxicity when examined for anticonvulsant activity using the seizure produced by maximal electroshock, following oral administration to rats."
11/01/2004 - "While the two ternary phenanthroline-containing complexes, 1 and 2, evidenced weak protection against maximal electroshock (MES)- and subcutaneous Metrazol (scMET) induced seizures, [Zn(II)(3,5-DIPS)(2)(DMSO)(2)], [Zn(II)(aspirinate)(2)(H(2)O)(2)], and bis(salicylato)-1,10-phenanthorlinezinc(II), [Zn(II)(salicylate)(2)(phen)], were found to be particularly useful in protecting against MES and scMET seizures and [Zn(II)(aspirinate)(2)(H(2)O)(2)] and [Zn(II)(salicylate)(2)(phen)] were found to have activity in protecting against Psychomotor seizures, without causing Rotorod toxicity. "
07/15/2000 - "Two binuclear copper(II) complexes of 3,5-diisopropylsalicylic acid were characterized by single crystal X-ray diffraction methods and examined for anti-inflammatory activity using activated polymorphonuclear leukocytes and for anticonvulsant activities using electroshock and metrazol models of seizures. "
01/01/1991 - "1. The effects of the octapeptide angiotensin II (AT II) on some types of behaviour [threshold of seizures induced by timed intravenous infusion of pentylenetetrazol (PTZ), exploratory behaviour: ambulation, rearing and head-dips on a hole-board, and passive avoidance performance--step-through paradigm] were studied following repeated systemic administration of MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) to mice (30 mg/kg, i.p., twice daily for 5 days). "
5. Apnea

Related Drugs and Biologics

1. Iodine
2. Pentylenetetrazole (Metrazol)
3. Progesterone
4. Prednisolone (Predate)
5. Dimethyl Sulfoxide (DMSO)
6. Bronchodilator Agents (Bronchodilators)
7. amitraz (Taktic)
8. diazenedicarboxylic acid bis(N'-methylpiperazide)
9. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
10. Chlorine

Related Therapies and Procedures

1. Renal Dialysis (Hemodialysis)
2. Ligation
3. Antibiotic Prophylaxis
4. Intensive Care (Surgical Intensive Care)
5. Stents