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cystinyl- aspartyl- prolyl- glycyl- tyrosyl- isoleucyl- glycyl- seryl- arginyl- NH2

synthetic laminin-derived peptide

Also Known As:

CDPGYIGSR-NH2; Cys-Asp-Pro-Gly-Tyr-Ile-Gly-Ser-Arg-NH2; laminin peptide 11

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - cystinyl-aspartyl-prolyl-glycyl-tyrosyl-isoleucyl-glycyl-seryl-arginyl-NH2: 3

Related Diseases

1.	Neoplasms (Cancer) 02/01/1991 - "It was concluded that solid tumor growth inhibition by CDPGYIGSR-NH2 was due not a direct effect on cell growth but to antiangiogenic effect mediated by the inhibition of endothelial cell migration." 12/15/1992 - "Peptide 11, CDPGYIGSR-NH2, is a segment of laminin which blocks tumor cell invasion. " 02/01/1991 - "A laminin-derived synthetic peptide, Cys-Asp-Pro-Gly-Tyr-Ile-Gly-Ser-Arg-NH2 (CDPGYIGSR-H2), containing an active site for cell binding inhibited both angiogenesis and solid tumor growth. " 02/01/1991 - "Inhibition of angiogenesis and tumor growth by a synthetic laminin peptide, CDPGYIGSR-NH2."
2.	Breast Neoplasms (Breast Cancer) 10/18/1996 - "A laminin-antagonist peptide, comprising amino acids 33-42 of murine epidermal growth factor (mEGF-(33-42)), interacts with a breast cancer- and endothelial cell-associated receptor, which is specific for the laminin B1 chain sequence, CDPGYIGSR-NH2 (Lam.B1-(925-933)), and is immunologically similar to a previously described 67-kDa laminin receptor. "

Related Drugs and Biologics

1.	Peptides (Polypeptides)
2.	Laminin (Merosin)
3.	Laminin Receptors
4.	Epidermal Growth Factor (EGF)
5.	Amino Acids