|1.||Denis, C: 1 article (03/2000)|
|2.||Dorner, F: 1 article (03/2000)|
|3.||Mihaly, J: 1 article (03/2000)|
|4.||Schwarz, H P: 1 article (03/2000)|
|5.||Turecek, P L: 1 article (03/2000)|
|6.||Lenting, P J: 1 article (03/2000)|
|7.||Binder, B: 1 article (03/2000)|
|1.||von Willebrand Diseases (von Willebrand's Disease)
09/01/1999 - "A recombinant preparation (rpvWF) containing both pro-vWF and mature vWF subunits was infused into 2 pigs and 1 dog with severe von Willebrand disease, 2 mice with a targeted disruption of the vWF gene, and 2 healthy baboons. "
09/01/1999 - "Evidence for extracellular processing of pro-von Willebrand factor after infusion in animals with and without severe von Willebrand disease."
03/01/2000 - "We used a murine model of severe von Willebrand disease (vWF knockout mice) to study the effect of a recombinant vWF/pro-vWF preparation (rpvWF) on factor VIII survival and to investigate whether low-density lipoprotein receptor-related protein (LRP) might be involved in the in vivo clearance of factor VIII in the absence of vWF. "
03/01/1995 - "The cleavage of pro-vWF by Dfurin2 shows that the previously reported lack of cleavage of the precursor of the beta A-chain of activin-A by Dfurin2 in this vaccinia expression system is substrate determined."
03/01/1995 - "In a vaccinia expression system, the endoprotease Dfurin2 not only cleaved wild-type precursor of von Willebrand factor (pro-vWF) with pro-region cleavage site R-S-K-R decreases, but also, although to a lesser extent, pro-vWF mutants in which the P2 (vWFK-2A) or P4 (vWFR-4A) basic residue with respect to the pro-region cleavage site had been mutated. "
|1.||LDL-Receptor Related Protein 1 (LDL-Receptor Related Protein)
|2.||Factor VIII (Coagulation Factor VIII)
|3.||von Willebrand Factor