HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

hemoglobin Johnstown

silent variant; Val replaced by Leu at position 109(G11) on the beta chain

Also Known As:

Hb Johnstown

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Blood Proteins: 12459
    - Hemoglobins: 37188
      - Abnormal Hemoglobins: 120
        hemoglobin Johnstown: 4
  - Hemeproteins: 194
    - Globins: 2716
      - Hemoglobins: 37188
        Abnormal Hemoglobins: 120
        hemoglobin Johnstown: 4

Experts

1.	Hoyer, James D: 1 article (01/2012)
2.	Inoue, Susumu: 1 article (01/2012)
3.	Oliveira, Jennifer L: 1 article (01/2012)
4.	Sharman, Mahesh: 1 article (01/2012)
5.	Eberle, Silvia Eandi: 1 article (01/2004)
6.	Feliu-Torres, Aurora: 1 article (01/2004)
7.	González, Silvia: 1 article (01/2004)
8.	Roldán, Ariel: 1 article (01/2004)
9.	Sciuccati, Gabriela: 1 article (01/2004)
10.	Anguita, E: 1 article (12/2000)

Related Diseases

1.	Polycythemia (Erythrocytosis) 01/01/2004 - "The erythrocytosis and low values for actual P50 due to Hb Johnstown were more marked due to the co-inheritance of the beta0-thal." 12/01/2000 - "In these cases the erythrocytosis and low values for P(50) due to Hb Johnstown remain in spite of the beta-thalassemia." 01/01/2012 - "Symptomatic erythrocytosis associated with a compound heterozygosity for Hb Lepore-Boston-Washington (δ87-β116) and Hb Johnstown [β109(G11)Val→Leu, GTG>TTG]." 01/01/1990 - "Hb Johnstown [beta 109 (G11) Val----Leu]: a new electrophoretically silent variant that causes erythrocytosis." 12/01/2000 - "Hb Johnstown, a high oxygen affinity hemoglobin, was identified in four members from two unrelated Spanish families with erythrocytosis and left-shifted hemoglobin-oxygen dissociation curve. "
2.	beta-Thalassemia (Cooley's Anemia) 12/01/2000 - "In these cases the erythrocytosis and low values for P(50) due to Hb Johnstown remain in spite of the beta-thalassemia."

Related Drugs and Biologics

1.	Oxygen (Dioxygen)
2.	Hemoglobins (Hemoglobin)
3.	valylleucine
4.	hemoglobin Lepore Boston-Washington