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8-methoxycaffeine

Also Known As:

8-MOC

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Alkaloids: 5398
  - Xanthines: 123
    - Caffeine: 7695
      - 8-methoxycaffeine: 2
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - Purinones: 2
        Xanthines: 123
        Caffeine: 7695
        8-methoxycaffeine: 2

Related Diseases

1.

Chromosome Aberrations (Chromosome Abnormalities)

06/01/1990 - "8-MOC has been postulated to produce chromosomal aberrations by DNA topoisomerase II inhibition. "
06/01/1990 - "8-methoxycaffeine (8-MOC) is a caffeine derivative more potent than its parental compound in inducing chromosomal aberrations. "
11/01/1994 - "We have studied the ability of 8-methoxycaffeine (8-MOC)--one of the most effective caffeine derivatives in inducing chromosomal aberrations--to induce DNA double strand breaks (DSB) in purified human T lymphocytes during the cell cycle. "

Related Drugs and Biologics

1.	Caffeine (No Doz)
2.	Type II DNA Topoisomerases (Topoisomerase II)
3.	DNA (Deoxyribonucleic Acid)
4.	1,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)