HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

exendin 3

from the gila monster lizard (Heloderma horridum); amino acid sequence given in first source

Also Known As:

exendin-3; Exendin 3

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - exendin 3: 4

Experts

1.	Gotthardt, Martin: 2 articles (07/2010 - 05/2002)
2.	Busa, Prabhakar: 1 article (09/2021)
3.	Kuthati, Yaswanth: 1 article (09/2021)
4.	Rao, Vaikar Navakanth: 1 article (09/2021)
5.	Wong, Chih-Shung: 1 article (09/2021)
6.	Deguchi, Hiroko: 1 article (01/2020)
7.	Enzan, Nobuyuki: 1 article (01/2020)
8.	Ide, Tomomi: 1 article (01/2020)
9.	Ikeda, Masataka: 1 article (01/2020)
10.	Ikeda, Soichiro: 1 article (01/2020)

Related Diseases

1.	Insulinoma 07/01/2010 - "68Ga-labelled exendin-3, a new agent for the detection of insulinomas with PET." 07/01/2010 - "Targeting of insulinomas with [Lys(40)(DOTA)]exendin-3 labelled with either (111)In or (68)Ga was investigated in vitro using insulinoma tumour cells (INS-1). " 07/01/2010 - "We investigated imaging of insulinomas with DOTA-conjugated exendin-3 labelled with (68)Ga. " 05/01/2002 - "It was also possible to detect insulinomas in an animal model by external scintigraphy using radioiodinated GLP-1 (7-36)amide and exendin 3. GLP-1 (7-36)amide is specifically internalised into insulinoma cells by a receptor-mediated mechanism. " 07/01/2010 - "The subcutaneous tumours were clearly visualized by small-animal PET imaging after injection of 3 MBq of [Lys(40)((68)Ga-DOTA)]exendin-3. [Lys(40)((68)Ga-DOTA)]Exendin-3 specifically accumulates in insulinomas, although the uptake is lower than that of [Lys(40)((111)In-DTPA)]exendin-3. Therefore, [Lys(40)((68)Ga-DOTA)]exendin-3 is a promising tracer to visualize insulinomas with PET."
2.	Hyperalgesia 09/09/2021 - "Seven days post PSNT, allodynia and hyperalgesia were confirmed as NP, and intrathecal (i.t) catheters were implanted and connected to an osmotic pump for the vehicle (1 μL/h) or TEN (5 μg/1 μL/h) or TEN (5 μg) + GLP-1R antagonist Exendin-3 (9-39) amide (EXE) 0.1 μg/1 μL/h infusion. "
3.	Cardiomegaly (Heart Hypertrophy) 01/01/2020 - "Exendin-3 (150 pmol/kg per minute), a GLP-1 (glucagon-like peptide 1) receptor antagonist, abrogated these inhibitory effects of teneligliptin on Nox4, 4-hydroxy-2-nonenal, phosphorylation of HDAC4, and cardiac hypertrophy. "

Related Drugs and Biologics

1.	Glucagon-Like Peptide 1 (GLP 1)
2.	Amides
3.	Peptides (Polypeptides)
4.	Pentetic Acid (DTPA)
5.	Glucagon-Like Peptide-1 Receptor
6.	3- (4- (4- (3- methyl- 1- phenyl- 1H- pyrazol- 5- yl)piperazin- 1- yl)pyrrolidin- 2- ylcarbonyl)thiazolidine
7.	1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid
8.	glucagon-like peptide 1 (7-36)amide
9.	4-hydroxy-2-nonenal (4-hydroxynonenal)

Related Therapies and Procedures

1.	Catheters