N-methylolacrylamide

bifunctional monomer possessing both vinyl & hydroxymethyl groups; used in adhesives, binders, surface coatings & resins; toxicity equals that of acrylamide

Also Known As:

Networked: 10 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Goffeng, Lars Ole: 2 articles (01/2008 - 08/2005)
2.	Kjuus, Helge: 2 articles (01/2008 - 08/2005)
3.	Skaug, Vidar: 2 articles (01/2008 - 08/2005)
4.	Chen, Qiang: 1 article (11/2021)
5.	Fang, Xiaohan: 1 article (11/2021)
6.	Kang, Qiong: 1 article (11/2021)
7.	Liu, Shuzheng: 1 article (11/2021)
8.	Qin, Gang: 1 article (11/2021)
9.	Yang, Jia: 1 article (11/2021)
10.	Zhang, Bin: 1 article (11/2021)

Related Diseases

1.	Carcinogenesis 09/01/1989 - "Toxicology and carcinogenesis studies were conducted by administering N-methylolacrylamide (98% pure) in water by gavage to groups of F344/N rats and B6C3F1 mice of each sex for 16 days, 13 weeks, or 2 years. " 09/01/1989 - "NTP Toxicology and Carcinogenesis Studies of N-Methylolacrylamide (CAS No. 924-42-5) in F344/N Rats and B6C3F1 Mice (Gavage Studies)."
2.	Necrosis 09/01/1989 - "Neurobehavioral studies indicated decreased forelimb grip strength in male and female mice at doses as low as 25 mg/kg. An exaggerated startle response was seen for female mice given 100 mg/kg. A reduction in rotarod performance was seen for male and female mice receiving 100 mg/kg and for male mice receiving 25 mg/kg. Hepatocellular necrosis anmale mice receiving 25 mg/kg. Hepatocellular necrosis and thymic lymphocytic necrosis were compound-related effects in mice given 200 mg/kg N-methylolacrylamide. "
3.	Neoplasms (Cancer) 09/01/1989 - "There was clear evidence of carcinogenic activity of N-methylolacrylamide for female B6C3F1 mice, based on increased incidences of neoplasms of the Harderian gland, liver, lung, and ovary. " 09/01/1989 - "There was clear evidence of carcinogenic activity of N-methylolacrylamide for male B6C3F1 mice, based on increased incidences of neoplasms of the Harderian gland, liver, and lung. " 12/01/2015 - "Gene expression analysis in the lung of the rasH2 transgenic mouse at week 4 prior to induction of malignant tumor formation by urethane and N-methylolacrylamide."
4.	Chromosome Aberrations (Chromosome Abnormalities) 08/01/2005 - "Chromosome aberrations in tunnel workers exposed to acrylamide and N-methylolacrylamide." 09/01/1989 - "N-Methylolacrylamide induced both sister chromatid exchanges (SCEs) and chromosomal aberrations in CHO cells with and without metabolic activation. "
5.	Atrophy 09/01/1989 - "Ovarian atrophy was observed at increased incidences in female mice receiving N-methylolacrylamide (3/50; 39/45; 38/47). " 06/01/1981 - "Atrophy was either prevented by phenobarbital treatment, as in the cases of acrylamide and N-isopropylacrylamide, or reduced, as in the case of N-hydroxymethylacrylamide. " 06/01/1981 - "Acrylamide, N-hydroxymethylacrylamide, N-isopropylacrylamide, N-methylacrylamide and N,N'-methylene-bis-acrylamide produced testicular atrophy. "

Related Drugs and Biologics

1.	N-methylacrylamide
2.	N-isopropylacrylamide
3.	Hydrogels
4.	Ethylene Glycol (Monoethylene Glycol)
5.	Urethane (Ethyl Carbamate)
6.	Phenobarbital (Luminal)
7.	Agar
8.	N,N'-methylenebisacrylamide