nooglutil

RN refers to (L)-isomer

Also Known As:

N-(5-hydroxynicotinyl)glutamic acid; N-5-(hydroxynicotinoyl)-L-glutamic acid; ONK 10; ONK-10; nooglutil, (DL)-isomer; nooglutyl; L-Glutamic acid, N-((5-hydroxy-3-pyridinyl)carbonyl)-

Networked: 10 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
  - Acidic Amino Acids: 44
    - Glutamates: 45
      - nooglutil: 10
  - Dicarboxylic Amino Acids: 20
    - Glutamates: 45
      - nooglutil: 10
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - Nicotinic Acids: 13
      - nooglutil: 10
- Heterocyclic Acids
  - Nicotinic Acids: 13
    - nooglutil: 10

Experts

1.	Voronina, T A: 3 articles (01/2004 - 01/2000)
2.	Galaeva, I P: 2 articles (01/2004 - 05/2003)
3.	Garibova, T L: 2 articles (01/2004 - 05/2003)
4.	Kraĭneva, V A: 2 articles (01/2004 - 05/2003)
5.	Iasnetsov, Vik V: 1 article (01/2013)
6.	Krylova, I N: 1 article (01/2013)
7.	Belozertsev, F Iu: 1 article (09/2007)
8.	Belozertsev, Iu A: 1 article (09/2007)
9.	Iuntsev, S V: 1 article (09/2007)
10.	Shabel'skaia, V V: 1 article (09/2007)

Related Diseases

1.	Hypoxia (Hypoxemia) 11/01/1995 - "[The correction with nooglutil and L-pyroglutamyl-D-alanine amide of cognitive disorders in rats due to intrauterine hypoxia]." 01/01/2000 - "The agents that combine a prevailing antiamnestic effect and a marked and moderate antihypoxic action (mexidole, nooglutil, pyracetam, beglymin, etc.) are most effective in eliminating different hypoxia-induced cognitive and memory disorders, nootropic drugs that have a pronounced antiamnestic activity (centrophenoxine, etc.) and no antihypoxic component also restore the main types of mnestic disorders after hypoxia, but to a lesser extent." 01/01/1998 - "The authors recommend novel nootrops (nooglutyl, mexidol, semax and GVS-111) for the pharmacological correction of mnestic disorders consequent to hypoxia or cerebral ischemia." 11/01/1995 - "Novel nootropic compounds, nooglutyl (N-5-hydroxy(nicotinoyl)-L-glutamine acid, 25 mg/kg/day) and L-pyroglutamyl-D-alanine amide (1 mg/kg/day) administered intracutaneously from the 8th to 20th day of life prevent from movement hyperactivity in "open field", disturbances in ability to training and in memory in an alternate test and in tests of passive and active avoidance and normalize behavior of the adult mail rats (subjected to two-hour hypobaric hypoxia in on the 15-day of intrauterine life, vacuum corresponded to the height 8500 m) in-extrapolation avoidance test. " 01/01/2013 - "It has been established in experiments in rats that some nootropic substances (oxyracetam, aniracetam, nooglutil, mexidol, new 3-hydroxypyridine derivative SK-170, piracetam and noopept) produce marked antiamnestic effect on various models of amnesia (induced by microwave irradiation, acute hypoxia, and motion sickness). "
2.	Memory Disorders (Memory Loss) 01/01/2000 - "The agents that combine a prevailing antiamnestic effect and a marked and moderate antihypoxic action (mexidole, nooglutil, pyracetam, beglymin, etc.) are most effective in eliminating different hypoxia-induced cognitive and memory disorders, nootropic drugs that have a pronounced antiamnestic activity (centrophenoxine, etc.) and no antihypoxic component also restore the main types of mnestic disorders after hypoxia, but to a lesser extent."
3.	Amnesia (Dissociative Amnesia) 05/01/2003 - "It was found that nootropes such as pyracetam, mexidol, semax, nooglutil, acephen, and noopept fully or completely prevent from the amnesia development." 01/01/2013 - "It has been established in experiments in rats that some nootropic substances (oxyracetam, aniracetam, nooglutil, mexidol, new 3-hydroxypyridine derivative SK-170, piracetam and noopept) produce marked antiamnestic effect on various models of amnesia (induced by microwave irradiation, acute hypoxia, and motion sickness). "
4.	Cognitive Dysfunction 11/01/1995 - "[The correction with nooglutil and L-pyroglutamyl-D-alanine amide of cognitive disorders in rats due to intrauterine hypoxia]."
5.	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 01/01/2004 - "[Effect of phenyl-tert-butylnitrone, mexidol and nooglutil on the ischemic lesion zone and memory in rats following middle cerebral artery occlusion]."

Related Drugs and Biologics

1.	Nootropic Agents (Nootropics)
2.	Piracetam (Nootropil)
3.	Meclofenoxate (Centrophenoxine)
4.	emoxypine succinate
5.	ethyl phenylacetyl-Pro-Gly
6.	Acids
7.	Pro-Gly-Pro- ACTH (4-7)
8.	alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)
9.	Potassium Magnesium Aspartate
10.	Glutamine (L-Glutamine)