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enterohemolysin

production associated with a temperate bacteriophage in E coli serogroup O26 strains; associated with enteric diseases

Also Known As:

entero-hemolysin

Networked: 11 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Pore Forming Cytotoxic Proteins
      - Hemolysin Proteins: 1059
        enterohemolysin: 11
  - Bacterial Proteins: 394
    - Escherichia coli Proteins: 12
      - enterohemolysin: 11

Experts

1.	Sun, Zhibin: 1 article (12/2022)
2.	Xu, Yan: 1 article (12/2022)
3.	Yao, Yu-Feng: 1 article (12/2022)
4.	Zhang, Wenting: 1 article (12/2022)
5.	Zhou, Ning: 1 article (12/2022)
6.	Heinisch, Laura: 1 article (01/2019)
7.	Schmidt, Herbert: 1 article (01/2019)
8.	Schwidder, Maike: 1 article (01/2019)
9.	Fischer, Markus: 1 article (11/2016)
10.	Hoffmann, Maria: 1 article (11/2016)

Related Diseases

1.	Hemolysis 10/01/2007 - "The aim of this study was to examine the DNA sequence of the gene for enterohemolysin, a plasmid-encoded toxin that readily causes the hemolysis of washed sheep erythrocytes, and to assess the distribution of enterohemolysin subtypes among E. " 12/01/2022 - "CsrA significantly represses plasmid-borne enterohemolysin (EhxA)-mediated hemolysis and activates chromosome-borne hemolysin E (HlyE)-mediated hemolysis through different mechanisms. "
2.	Infections 01/01/2012 - "The role of EHEC O157:H7-enterohemolysin (Ehx) in the pathogenesis of infections remains poorly defined. " 07/31/2002 - "Although most clinical isolates of STEC produce hemolysin (called enterohemolysin), the precise role of enterohemolysin in the pathogenesis of STEC infections is unknown. " 08/01/1990 - "vulgaris strains isolated in acute enteric infections in children for producing enterohemolysin, a new type of hemolysin, has been shown. "
3.	Hemolytic-Uremic Syndrome 11/01/2016 - "Most Shiga toxin-producing Escherichia coli (STEC) strains associated with severe disease, such as hemolytic-uremic syndrome (HUS), carry large enterohemolysin-encoding (ehxA) plasmids, e.g., pO157 and pO103, that contribute to STEC clinical manifestations. " 07/01/2004 - "Shiga toxin-producing Escherichia coli (STEC) strains possessing genes for enterohemolysin (ehxA) and/or intimin (eae), referred to here as complex STEC (cSTEC), are more commonly recovered from the feces of humans with hemolytic uremic syndrome and hemorrhagic colitis than STEC strains that do not possess these accessory virulence genes. " 01/01/2019 - "The ability to produce enterohemolysin is regarded as a potential virulence factor for enterohemorrhagic Escherichia coli (EHEC) and is frequently associated with severe human diseases such as hemorrhagic colitis (HC) and the hemolytic uremic syndrome (HUS). "
4.	Colitis 07/01/2004 - "Shiga toxin-producing Escherichia coli (STEC) strains possessing genes for enterohemolysin (ehxA) and/or intimin (eae), referred to here as complex STEC (cSTEC), are more commonly recovered from the feces of humans with hemolytic uremic syndrome and hemorrhagic colitis than STEC strains that do not possess these accessory virulence genes. " 01/01/2001 - "Enterohemolysin, serine protease, causing disturbances in the barrier function of the intestine, can be regarded in the pathogenesis of hemorrhagic colitis which develops as the result of the damaging action of EHEC and the above-mentioned toxins. " 01/01/2019 - "The ability to produce enterohemolysin is regarded as a potential virulence factor for enterohemorrhagic Escherichia coli (EHEC) and is frequently associated with severe human diseases such as hemorrhagic colitis (HC) and the hemolytic uremic syndrome (HUS). "
5.	Diarrhea 07/15/2014 - "Diarrheagenic Escherichia coli (DEC), including Enterotoxigenic E.coli (ETEC), Enteroaggregative E.coli (EAEC), Enteropathogenic E.coli (EPEC), Enterohemolysin E.coli (EHEC) and Enteroinvasive E.coli (EIEC) causes diarrhea or hemolytic uremic syndromes among infants and travelers around the world. " 11/01/2003 - "Enterohemolysin produced by Escherichia coli associated with infant diarrhea showed characteristics similar to those of thiol-activated hemolysins produced by Gram-positive bacteria, including inactivation by cholesterol, lytic activity towards eukaryotic cells and thermoinstability. "

Related Drugs and Biologics

1.	Hemolysin Proteins (Hemolysins)
2.	Serine Proteases (Serine Protease)
3.	Virulence Factors (Pathogenicity Factors)
4.	Sulfhydryl Compounds (Thiols)
5.	Cholesterol