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pyrimidoxime

structure given in first source; RN given refers to the dibromide; RN for parent cpd not available 11/90

Also Known As:

1-(1-methylimidazolinium)-3-(4-carbaldoximepyridinium)propane

Networked: 3 relevant articles (2 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Imidazoles: 150
      - pyrimidoxime: 3
  - Pyridines: 88
    - Pyridinium Compounds: 5
      - pyrimidoxime: 3

Related Diseases

1.	Poisoning 01/01/1992 - "Efficacy of HLö-7 and pyrimidoxime as antidotes of nerve agent poisoning in mice." 07/01/1990 - "Soman and A4 poisoning do not modify the kinetic parameters of pyrimidoxime, but A4 poisoning increases HI6 tissue concentration. " 01/01/1992 - "HLö-7 was very effective against tabun poisoning while HI-6 and pyrimidoxime were of moderate value. " 01/01/1992 - "In contrast, pyrimidoxime was a relatively poor therapy which resulted in ED50 values of greater than 150, 5.88, 100 and 71 mg/kg against poisoning by soman, sarin, GF and tabun, respectively. "
2.	Organophosphate Poisoning 07/01/1990 - "Disposition and metabolism of two acetylcholinesterase reactivators, pyrimidoxime and HI6, in rats submitted to organophosphate poisoning."

Related Drugs and Biologics

1.	tabun
2.	Nerve Agents
3.	asoxime chloride (H16)
4.	Soman
5.	Sarin
6.	Acetylcholinesterase

Related Therapies and Procedures

1.	Therapeutics