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ampiroxicam

prodrug of piroxicam; structure given in first source

Also Known As:

(+-)-4-(1-hydroxyethoxy)-2-methyl-N-2-pyridyl-2H-1,2- benzothiazine-3-carboxamide ethyl carbonate (ester), 1,1- dioxide

Networked: 6 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Sulfur Compounds: 278
  - Thiazines: 3
    - ampiroxicam: 6
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Thiazines: 3
    - ampiroxicam: 6

Experts

1.	Cho, N-P: 1 article (07/2011)
2.	Cho, S-D: 1 article (07/2011)
3.	Choi, K-H: 1 article (07/2011)
4.	Huong, L D: 1 article (07/2011)
5.	Shim, J-H: 1 article (07/2011)
6.	Fujii, K: 1 article (08/2001)
7.	Hiranuma, K: 1 article (08/2001)
8.	Nemoto, T: 1 article (08/2001)
9.	Sai, S: 1 article (08/2001)
10.	Sato, T: 1 article (08/2001)

Related Diseases

1.	Mucoepidermoid Carcinoma 07/01/2011 - "The aim of this study was to evaluate the role of tolfenamic acid (Tol) and ampiroxicam (Amp) in the apoptotic regulation of YD-15 salivary mucoepidermoid carcinoma (MEC). "
2.	Postoperative Pain 08/01/2001 - "Preoperative ampiroxicam reduces postoperative pain after hand surgery." 08/01/2001 - "We performed a double blind randomised controlled study to assess whether the preoperative administration of ampiroxicam reduced the level of postoperative pain in 120 patients who underwent surgery to a hand under brachial plexus block. " 08/01/2001 - "We found that preoperative (pre-emptive) administration of ampiroxicam significantly reduced the postoperative pain levels and the need for postoperative analgesia."
3.	Contact Dermatitis (Eczema, Contact) 11/01/1999 - "Antigenic characterization in ampiroxicam-induced photosensitivity using an in vivo model of contact hypersensitivity." 01/01/1999 - "In our previous report, however, ultraviolet-A (UVA)-irradiated or non-irradiated PXM did not induce any reactions in the in vivo model of contact hypersensitivity, while positive patch testing was shown by ampiroxicam (APX; a prodrug of PXM). " 01/01/1999 - "Differential property of antigenic characterization between piroxicam and ampiroxicam in contact hypersensitivity."
4.	Membranous Glomerulonephritis (Membranous Nephropathy) 01/01/1999 - "Membranous nephropathy induced by treatment with ampiroxicam, a nonsteroidal antiinflammatory drug."
5.	Inflammation (Inflammations) 07/01/1993 - "In an acute model of paw inflammation in rats, ampiroxicam is less potent than piroxicam itself: the ED50's of ampiroxicam are 9- and 3.5-fold higher than those of piroxicam following a single or multiple (5) daily oral doses, respectively. "

Related Drugs and Biologics

1.	Adenosine Monophosphate (AMP)
2.	tolfenamic acid
3.	Piroxicam (Feldene)
4.	Prodrugs

Related Therapies and Procedures

1.	Brachial Plexus Block
2.	Analgesia