batroxostatin

from venom of Bothrops atrox; contains 71 amino acids; potent inhibitor of fibrinogen-mediated platelet aggregation & fibronectin-mediated adhesion of melanoma cells; amino acid sequence given in first source

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.

Melanoma (Melanoma, Malignant) 09/24/1990 - "The anti-GP140 antibody, recognizing beta 1 integrins, completely inhibited adhesion of mouse melanoma cells to batroxostatin. " 09/24/1990 - "Batroxostatin covalently attached to plastic promoted adhesion of melanoma cells. " 09/24/1990 - "In addition, batroxostatin was about 400-times more potent than GRGDS at inhibiting melanoma cell adhesion to fibronectin. "

Related Drugs and Biologics

1.	Integrins
2.	Plastics
3.	Fibronectins (Fibronectin)
4.	glycyl-arginyl-glycyl-aspartyl-serine