losigame (A033)

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8 relevant articles (1 outcomes, 5 trials/studies) found for this Bio-Agent

Description: tetronic acid derivative

Also Known As:

A033; losigamone; AO-33; (5RS)-(alphaSR)-5-(2-chlorophenylhydroxymethyl)-4-methoxy-2(5H)-furanone; 5-(2-chlorophenylhydroxymethyl)-4-methoxy-2-(5H)-furanone; A 033; A-033; ADD137022

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 23

1-Ring Heterocyclic Compounds

Furans: 33

losigame: 8

Experts

1.	Losigamone Study Group: 2 articles (08/2003 - 04/2001)
2.	Dienel, A: 2 articles (10/2001 - 04/2001)
3.	Borowicz, Kinga K: 1 article (09/2003)
4.	Piskorska, Barbara: 1 article (09/2003)
5.	Małek, Robert: 1 article (09/2003)
6.	Kimber-Trojnar, Zaneta: 1 article (09/2003)
7.	Czuczwar, Stanisław J: 1 article (09/2003)
8.	Sobieszek, Grzegorz: 1 article (09/2003)
9.	Klement, S: 1 article (08/2003)
10.	Baulac, M: 1 article (08/2003)

Related Diseases

1.	Seizures (Seizure) 08/01/2003 - "The objective of the study was to investigate the efficacy and safety of two different dosages of Losigamone (LSG) in add-on treatment of partial seizures" 10/01/2001 - "METHODS: Sixteen patients with pharmacoresistant partial seizures undergoing presurgical evaluation were randomized in this double-blind, placebo-controlled, parallel-group Losigamone monotherapy study under continuous video-EEG monitoring" 11/01/1999 - "This study investigated the effects of the S(+)- and R(-)- enantiomers of losigamone on endogenous amino acid release from BALB/c mouse cortical slices, spontaneous depolarizations in the cortical wedge preparation of the DBA/2 mouse and audiogenic seizures in DBA/2 mice" 11/01/1999 - "1 Losigamone is a novel anticonvulsant undergoing phase III clinical trials in patients with partial and secondary generalized seizures" 09/01/2003 - "In clinical trial, losigamone proved to have satisfactory effectiveness and good tolerance in the treatment of partial and secondary generalized seizures" Get all the results and reference details, order at left...
2.	Partial Epilepsies (Epilepsy, Partial) 04/01/2001 - "Losigamone add-on therapy in partial epilepsy: a placebo-controlled study." Get all the results and reference details, order at left...
3.	Epilepsy (Aura) 09/01/2003 - "Perspectives of losigamone in epilepsy treatment." Get all the results and reference details, order at left...
3 Diseases and 8 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	Vigabatrin
2.	Cocaine (Cocaine HCl)
3.	remacemide
4.	loreclezole
5.	tiagabine (Gabitril)
6.	felbamate (Felbatol)
7.	gabapentin (Neurontin)
8.	stiripentol
9.	progabide (Gabrene)
10.	alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)
12 Drugs and Important Bio-Agents and 3 more articles analyzed in the Research Interface, order at left...

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