|1.||Alonso, Silvia Del V: 1 article (12/2012)|
|2.||Temprana, C Facundo: 1 article (12/2012)|
|3.||Grasselli, Mariano: 1 article (12/2012)|
|4.||Amor, María Silvia: 1 article (12/2012)|
|5.||Femia, A Lis: 1 article (12/2012)|
|6.||Santos, Javier: 1 article (12/2012)|
|7.||Carbajal, María Laura: 1 article (12/2012)|
|8.||Lam, Dennis S C: 1 article (07/2012)|
|9.||Tham, Clement C Y: 1 article (07/2012)|
|10.||Martin, Frank J: 1 article (07/2012)|
06/20/2009 - "High expression of APAO can greatly decrease the sensitivity of tumor cells to the specific polyamine analogues by detoxifying those analogues and prevent analogue induced apoptosis."
06/20/2009 - "Recent studies have demonstrated in vitro that some antitumor polyamine analogues could be used as substrates and oxidized by purified recombinant human N(1)-acetylpolyamine oxidase (APAO, an enzyme that catabolizes natural polyamines), indicating a potential role of APAO in determining the sensitivity of cancer cells to specific antitumor analogues. "
12/01/2012 - "The use of APAO-FITC in the identification of different protein and cell targets, as well as in in vivo biodistribution studies, conformational studies of arsenic-binding proteins, and studies for the design of drug delivery systems for arsenic anti-cancer therapies, is highly promising."
|2.||Lung Neoplasms (Lung Cancer)
06/20/2009 - "This study evaluated, in vivo, the effect of APAO on cytotoxicity of antitumor polyamine analogue, N(1)-cyclopropylmethyl-N(11)-ethylnorspermine (CPENS) and its mechanism when highly expressed in human lung cancer line A549. "
06/20/2009 - "A clone with high expression of APAO was obtained by transfecting A549 lung cancer cell line with pcDNA3.1/APAO plasmid and selecting with quantitative realtime PCR and APAO activity assay. "
|3.||Blindness (Hysterical Blindness)
|3.||Carrier Proteins (Binding Protein)
|5.||human N(1)-acetylpolyamine oxidase