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N(6)-(amido-3-propyl)adenosine
increases plasma corticosterone in normal rats by acting on adenosine A2 receptors in the pituitary
Also Known As:
Agr 529; Agr-529; Adenosine, N-(4-amino-4-oxobutyl)-, hydrochloride
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Purines: 651
Purine Nucleosides: 360
Adenosine: 12431
N(6)-(amido-3-propyl)adenosine: 1
Nucleic Acids, Nucleotides, and Nucleosides: 1
Nucleosides: 6847
Purine Nucleosides: 360
Adenosine: 12431
N(6)-(amido-3-propyl)adenosine: 1
Ribonucleosides: 49
Adenosine: 12431
N(6)-(amido-3-propyl)adenosine: 1
Related Diseases
1.
Hypertriglyceridemia
03/01/1992 - "
Using a model of hypertriglyceridemia provoked by intravenous injection of Triton WR 1339, we observed that Agr 529 [N6(amido-3-propyl)adenosine hydrochloride] at 2 mg.kg-1 intravenous in rabbits, and intraperitoneally and orally in rats led to a return of the levels of circulating triglycerides to normal values.
"
03/01/1992 - "
The present results show that the administration of Agr 529 and Agr 540 to normal animals causes hypolipemia (decrease in fatty acids, phospholipids, triglycerides and cholesterol) and restores induced hypertriglyceridemia.
"
Related Drugs and Biologics
1.
Triglycerides (Triacylglycerol)
2.
Phospholipids (Phosphatides)
3.
Fatty Acids (Saturated Fatty Acids)
4.
Cholesterol
5.
Adenosine (Adenocard)
6.
Agr 540
7.
tyloxapol
Related Therapies and Procedures
1.
Intravenous Injections