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N- (8- amino- 1- carboxyoctyl)- alanyl- proline (AB 47)

structure given in first source

Also Known As:

AB 47; AB-47; L-Proline, 1-(N-(8-amino-1-carboxyoctyl)-L-alanyl)-, (S)-

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - Dipeptides: 945
      - N-(8-amino-1-carboxyoctyl)-alanyl-proline: 5

Experts

1.	Jia, Yu: 1 article (12/2021)
2.	Wang, Hui-Fang: 1 article (12/2021)
3.	Wang, Yu-Ping: 1 article (12/2021)
4.	Zhang, Meng-Yao: 1 article (12/2021)
5.	Baan, J: 1 article (02/2011)
6.	Ballieux, B: 1 article (02/2011)
7.	Martín-Martorell, P: 1 article (02/2011)
8.	Radder, J K: 1 article (02/2011)
9.	Smit, J W A: 1 article (02/2011)
10.	de Graaff, L C G: 1 article (02/2011)

Related Diseases

1.	Hypothyroidism 02/01/2011 - "The occurrence of (sub)clinical hypothyroidism was higher in patients with Tg-Ab (47%) or TPO-Ab (42%) than in those without these antibodies (6.2 and 5.1%, respectively, p<0.001). "
2.	Hypertension (High Blood Pressure) 12/01/1990 - "These results suggest that AB-47 is a potent and long-lasting hypotensive agent and may be useful for the therapy of both hypertension and congestive heart failure."
3.	Heart Failure 12/01/1990 - "These results suggest that AB-47 is a potent and long-lasting hypotensive agent and may be useful for the therapy of both hypertension and congestive heart failure."
4.	Cardiomegaly (Heart Hypertrophy) 11/01/1993 - "The potentiation of edema may be due to an accumulation of bradykinin induced by the inhibition of angiotensin converting enzyme (ACE), because ACE is the identical enzyme with kinase II. The pretreatment of AB-47 for 7 days (1, 3, 10 mg/kg/d p.o.) inhibited the cardiac hypertrophy induced by isoproterenol (isoprenaline). "
5.	Glioma (Gliomas) 12/09/2021 - "Of the 915 patients, 191 patients were positive for neural-surface specific antibodies (115 N-methyl-D-aspartate receptor (NMDAR) Ab, 47 leucine-rich glioma-inactivated protein 1 (LGI1) Ab, 8 contactin-associated protein 2 (CASPR2) Ab, 4 AMPA2R-Ab, and 11 GABAR-B-Ab; 3 CASPR2-Ab and LGI1-Ab, 2 NMDAR-Ab and CASPR2-Ab, and 1 NMDAR-Ab and myelin-oligodendrocyte glycoprotein [MOG] Ab). "

Related Drugs and Biologics

1.	Antibodies
2.	Myelin-Oligodendrocyte Glycoprotein
3.	N-Methyl-D-Aspartate Receptors (NMDA Receptors)
4.	Proteins (Proteins, Gene)
5.	Phosphotransferases (Kinase)
6.	Leucine (L-Leucine)
7.	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)
8.	Isoproterenol (Isoprenaline)
9.	Enzymes
10.	Carrageenan

Related Therapies and Procedures

1.	Therapeutics