2- (2- (1- phenyl- 4- piperazynyl)ethyl)- 1,2,3,4- tetrahydro- beta- carboline- 1- spiro- 4'- N'- benzylpiperidine

08/01/1999 - "This study assessed the efficacy of physical examination as a screening modality for the diagnosis of surgically significant arterial injury in proximity penetrating extremity trauma (PPET). "
12/01/1995 - "Over 18 months, we prospectively screened 37 patients (43 lower extremities) with PPET for occult arterial and venous injuries using noninvasive studies (physical examination, ankle-brachial indices, color-flow duplex ultrasonography (CFD)) and angiography (arteriography, venography). "
01/01/2014 - "Occult venous injuries as a result of PPET occur in 4.8% of patients with thigh wounds in proximity to a major vascular structure. "
08/01/1999 - "Four hundred twenty-one extremities with PPET fell into Group 1. There were four missed injuries (specificity, 99%) in this group (one ulnar artery, one radial artery, one posterior tibial artery, and one anterior tibial artery). "
12/01/1995 - "We conclude that following PPET, (1) isolated, occult venous injuries are common and are associated with significant complications and (2) CFD is useful for screening for occult venous injuries."

01/01/2004 - "The effect of PPEt at 200 mg/kg of body weight was better than that of glibenclamide."
01/01/2002 - "The effect of PPEt at 200 mg/kg body weight was more effective than glibenclamide."
01/01/2002 - "Oral administration of Phaseolus vulgaris pod extract (PPEt; 200 mg/kg body weight) for 45 days resulted in a significant reduction in thiobarbituric acid reactive substances and hydroperoxides. "
01/01/2006 - "Ethanolic extract of Pongamia pinnata (PPEt) leaves was administered orally (300 mg/kg body weight) and the effects of PPEt on the levels of thiobarbituric acid reactive substances (TBARS), hydroperoxides (HP), conjugated diene (CD), superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), and reduced glutathione (GSH) were studied in liver and kidney of ammonium chloride-induced hyperammonemic rats. "
01/01/2002 - "vulgaris pods (PPEt, 200 mg/kg body weight) for 45 days significantly reduced the elevated blood glucose, serum triglycerides, free fatty acids, phospholipids, total cholesterol, very-low-density lipoprotein cholesterol, and low-density lipoprotein cholesterol. "

12/01/2016 - "In conclusion, Serelaxin improved blood pressure, sFlt-1, TNF-α, UARI, and nitric oxide bioavailability and PPET-1 in a rat model of preeclampsia, thereby suggesting a potential therapeutic role for RLX in maintaining maternal health and prolonging pregnancy in the face of placental ischemia."

12/01/2016 - "In conclusion, Serelaxin improved blood pressure, sFlt-1, TNF-α, UARI, and nitric oxide bioavailability and PPET-1 in a rat model of preeclampsia, thereby suggesting a potential therapeutic role for RLX in maintaining maternal health and prolonging pregnancy in the face of placental ischemia."

08/01/1999 - "Patients admitted with PPET fell into one of three categories: 1) no hard signs of vascular injury present-admitted for 24-hour observation; 2) presence of at least one hard sign of vascular injury-taken immediately to the operating room; 3) positive sign of arterial injury that requires angiography (i.e., diminished but appreciable pulse by physical examination or doppler, large nonexpanding hematoma, bilateral pulse deficit, no appreciable pulse with unreconstructable trajectory). "
12/01/1995 - "The diagnosis and management of occult vascular injuries caused by penetrating proximity extremity trauma (PPET) remains controversial. "
08/01/1989 - "Although "soft" clinical signs were significantly more predictive of vascular injury following PPET than proximity alone (p less than 0.0005), 50% of all injuries to major arteries did not manifest soft signs. "