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p21(ras) farnesyl-protein transferase (protein farnesyltransferase)

transfers the farnesyl moiety from farnesyl pyrophosphate to a cysteine in p21(ras) proteins; composed of an alpha and a beta subunit
Also Known As:
protein farnesyltransferase; CAAX farnesyltransferase; FT alpha; FT beta; Ftase enzyme; PC farnesyltransferase; farnesyl-protein transferase p21(ras); farnesyl-protein transferase-alpha; farnesyl-protein transferase-beta; p21(ras) farnesyltransferase; protein-cysteine farnesyltransferase; ras p21 farnesyl-protein transferase
Networked: 43 relevant articles (5 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Young, Stephen G: 7 articles (02/2013 - 07/2005)
2. Fong, Loren G: 6 articles (02/2013 - 07/2005)
3. Yang, Shao H: 6 articles (02/2013 - 07/2005)
4. Gelb, Michael H: 6 articles (01/2008 - 08/2002)
5. Beese, Lorena S: 5 articles (11/2008 - 07/2003)
6. Van Voorhis, Wesley C: 4 articles (01/2008 - 08/2002)
7. Yokoyama, Kohei: 4 articles (01/2008 - 08/2002)
8. Buckner, Frederick S: 4 articles (02/2006 - 08/2002)
9. Bergo, Martin O: 3 articles (04/2010 - 07/2005)
10. Meta, Margarita: 3 articles (10/2006 - 07/2005)

Related Diseases

1. Progeria (Hutchinson Gilford Syndrome)
2. Bone Diseases (Bone Disease)
3. Neoplasms (Cancer)
4. Malaria
5. Carcinogenesis

Related Drugs and Biologics

1. lonafarnib (SCH 66336)
2. Proteins (Proteins, Gene)
3. Blood Proteins (Serum Proteins)
4. geranylgeranyltransferase type-I (protein geranylgeranyltransferase)
5. Enzymes
6. Dehydroepiandrosterone Sulfate
7. Lipids
8. tipifarnib (R115777)
9. Farnesyltranstransferase (Farnesyltransferase)
10. Monomeric GTP-Binding Proteins

Related Therapies and Procedures

1. Therapeutics
2. Microspheres (Microsphere)
3. Radiotherapy
4. Photochemotherapy (Photodynamic Therapy)
5. Immunotherapy