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p21(ras) farnesyl-protein transferase (protein farnesyltransferase)

transfers the farnesyl moiety from farnesyl pyrophosphate to a cysteine in p21(ras) proteins; composed of an alpha and a beta subunit
Also Known As:
protein farnesyltransferase; CAAX farnesyltransferase; FT alpha; FT beta; Ftase enzyme; PC farnesyltransferase; farnesyl-protein transferase p21(ras); farnesyl-protein transferase-alpha; farnesyl-protein transferase-beta; p21(ras) farnesyltransferase; protein-cysteine farnesyltransferase; ras p21 farnesyl-protein transferase
Networked: 33 relevant articles (2 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Gelb, Michael H: 5 articles (01/2008 - 08/2002)
2. Van Voorhis, Wesley C: 4 articles (01/2008 - 08/2002)
3. Yokoyama, Kohei: 4 articles (01/2008 - 08/2002)
4. Buckner, Frederick S: 4 articles (02/2006 - 08/2002)
5. Yang, Shao H: 3 articles (04/2010 - 10/2006)
6. Young, Stephen G: 3 articles (04/2010 - 10/2006)
7. Beese, Lorena S: 3 articles (09/2008 - 07/2003)
8. Bergo, Martin O: 2 articles (04/2010 - 10/2006)
9. Fong, Loren G: 2 articles (02/2010 - 10/2006)
10. Grellier, Philippe: 2 articles (01/2010 - 10/2005)

Related Diseases

1. Neoplasms (Cancer)
2. Progeria (Hutchinson Gilford Syndrome)
3. Malaria
4. African Trypanosomiasis (Nagana)
5. Parasitic Diseases (Parasitic Disease)

Related Drugs and Biologics

1. Proteins (Proteins, Gene)
2. Dehydroepiandrosterone Sulfate
3. tipifarnib (R115777)
4. geranylgeranyltransferase type-I (protein geranylgeranyltransferase)
5. Farnesyltranstransferase (Farnesyltransferase)
6. Transferases
7. Tetrahydrofolate Dehydrogenase (Dihydrofolate Reductase)
8. Peptide Hydrolases (Proteases)
9. Hemoglobins (Hemoglobin)
10. Heme (Haem)

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Therapeutics
3. Radiotherapy
4. Drug Therapy (Chemotherapy)