PKSI 527
structure given in first source
Also Known As:
Benzeneacetic acid, 4-((2-(((4-(aminomethyl)cyclohexyl)carbonyl)amino)-1-oxo-3-phenylpropyl)amino)-, monohydrochloride, (1(S)-trans)-; N-(4-aminomethylcyclohexylcarbonyl)phenylalanyl-4-carboxymethylanilide; PKSI-527; t-AMCHA-Phe-p-APAA; trans-4-aminomethylcyclohexanecarbonyl-D-phenylalanine-4-carboxymethylanilide
Networked: 3
relevant articles (1 outcomes,
2 trials/studies)
for this Bio-Agent,
Comments
Relationship Network
Bio-Agent Context: Research Results
Experts
| 1. | Souccar, Caden: 1 article (12/2004) |
| 2. | Puzer, Luciano: 1 article (12/2004) |
| 3. | Oliveira, Vitor: 1 article (12/2004) |
| 4. | Moura-da-Silva, Ana Maria: 1 article (12/2004) |
| 5. | Lopes-Ferreira, Mônica: 1 article (12/2004) |
| 6. | Lapa, Antônio José: 1 article (12/2004) |
| 7. | Juliano, Luiz: 1 article (12/2004) |
| 8. | Emim, José Artur da Silva: 1 article (12/2004) |
| 9. | Cezari, Maria Helena: 1 article (12/2004) |
| 10. | Araújo, Mariana da Silva: 1 article (12/2004) |
Related Diseases
| 1. | Arthritis (Polyarthritis)
05/01/1993
- "PKSI-527, as well as indomethacin, reduced the severity of arthritis significantly. "
Order ALL the reference details at left... |
| 2. | Inflammation
|
| 3. | Disseminated Intravascular Coagulation
05/15/1996
- "This study was conducted to evaluate PKSI-527, on thromboplastin (TP)- and endotoxin (LPS)-induced disseminated intravascular coagulation (DIC) in rats. "
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| 4. | Experimental Arthritis
05/01/1993
- "A study was conducted to evaluate the effects of a new, highly selective plasma kallikrein inhibitor, PKSI-527, on collagen-induced arthritis (CIA) in mice. "
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| 5. | Edema
12/01/2004
- "Administration of a specific plasma kallikrein inhibitor (PKSI(527,) 100 mg/kg, s.c.) did not affect the venom-induced nociceptive response, but it decreased the paw edema by 15% from control. "
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Related Drugs and Biologics
| 1. | Indomethacin (Indometacin)
|
| 2. | Plasma Kallikrein
|
| 3. | Thromboplastin (Tissue Factor)
|
| 4. | Dacarbazine (DIC)
|
| 5. | Venoms
|
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