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desethyl KB 3022

metabolite of KB 3022; structure given in first source

Also Known As:

2-(4,5-bis(4-methoxylphenyl)thiazol-2-yl)pyrrol-1-ylacetic acid; desethyl KB-3022; desethyl KBT-3022

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Thiazoles: 392
      - desethyl KB 3022: 1
    - Pyrroles: 369
      - desethyl KB 3022: 1
Organic Chemicals: 133
- Sulfur Compounds: 278
  - Thiazoles: 392
    - desethyl KB 3022: 1

Related Diseases

1.

Thrombosis (Thrombus)

06/11/1997 - "On the other hand, aspirin (10 and 30 mg/kg, i.v.) had little effect in terms of preventing thrombosis, although it inhibited collagen-induced platelet aggregation to the same extent as did desethyl KBT-3022. "
06/11/1997 - "The antithrombotic effect of desethyl KBT-3022, which is the main active metabolite of the new antiplatelet agent, KBT-3022 (ethyl 2-[4,5-bis(4-methoxyphenyl)thiazol-2-yl] pyrrol-1-ylacetate; a cyclooxygenase inhibitor), was determined using a photochemically induced arterial thrombosis model in the rat femoral artery. "
06/11/1997 - "Antithrombotic effects in a rat model of aspirin-insensitive arterial thrombosis of desethyl KBT-3022, the main active metabolite of a new antiplatelet agent, KBT-3022."

Related Drugs and Biologics

1.	Cyclooxygenase Inhibitors
2.	Platelet Aggregation Inhibitors (Antiplatelet Drugs)
3.	Collagen
4.	Aspirin (Acetylsalicylic Acid)
5.	KB 3022