isoacteoside

a phenylethanoid glycoside isolated from Indian paintbrush (Verbenaceae) Castilleja linariaefolia; also in other plants; structure given in first source

Also Known As:

isoacetoside; isoverbascoside; beta-D-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl 3-O-(6-deoxy-alpha-L-mannopyranosyl)-, 6-(3-(3,4-dihydroxyphenyl)-2-propenoate), (E)-

Networked: 15 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Li, Ji: 2 articles (09/2017 - 11/2002)
2.	Banerjee, Sanjay Kumar: 1 article (12/2021)
3.	Barge, Sagar Ramrao: 1 article (12/2021)
4.	Bharadwaj, Simanta: 1 article (12/2021)
5.	Borah, Jagat C: 1 article (12/2021)
6.	Boruwa, Joshodeep: 1 article (12/2021)
7.	Deka, Barsha: 1 article (12/2021)
8.	Dutta, Partha Pratim: 1 article (12/2021)
9.	Ghosh, Aparajita: 1 article (12/2021)
10.	Kamboj, Parul: 1 article (12/2021)

Related Diseases

1.	Ovarian Neoplasms (Ovarian Cancer) 01/01/2019 - "The purpose of the present study was to investigate the anticancer properties of isoacteoside against OVCAR-3 human ovarian cancer cells. " 01/01/2019 - "Isoacteoside exerted both dose-dependent as well as time-dependent growth inhibitory effects on ovarian cancer cells with IC50 values of 15 µM at 24h incubation. " 01/01/2019 - "Suppression of in vitro and in vivo human ovarian cancer growth by isoacteoside is mediated via sub-G1 cell cycle arrest, ROS generation, and modulation of AKT/PI3K/m-TOR signalling pathway." 01/01/2019 - "In brief, the current study indicates that isoacteoside has a great potential in suppressing both in vitro and in vivo ovarian cancer cell growth and can be used as a possible anticancer agent."
2.	Acute Kidney Injury (Acute Renal Failure) 01/01/2021 - "Isoacteoside attenuates acute kidney injury induced by severe acute pancreatitis." 09/01/2017 - "The in vivo anti-inflammatory effect of isoacteoside was determined using mouse models of xylene-induced ear oedema, LPS-induced endotoxic shock and LPS-induced endotoxaemia-associated acute kidney injury (AKI). "
3.	Hepatocellular Carcinoma (Hepatoma) 04/01/2002 - "Here we report that isoverbascoside is capable of inducing differentiation in human hepatocellular carcinoma (HCC) cell line SMMC-7721. " 06/18/2008 - "Gekko sulfated polysaccharides, isoverbascoside, Ginsenoside-Rh2, Camptothecin, 9-nitro-camptothecin, tachyplesin, Matrine, tylophorine, 7-OH-4-CH(3)-coumarin and arsenic trioxide are known to have a differentiation-inducing capability on hepatocellular carcinoma in vitro and/or in vivo. "
4.	Carcinogenesis 12/01/1999 - "Granular differentiation of HL-60 cells was induced by isoverbascoside at 20-25 mumol/L within 1-3 days as the results of morphological changes, enhancement of phagocytosis and decreasing of tumorigenesis. "
5.	Cognitive Dysfunction 04/24/2017 - "We suggest that acteoside and isoacteoside ameliorated the cognitive dysfunction that was caused by Aβ 1-42 by blocking amyloid deposition via preventing amyloid oligomerization, and reversing central neuronal function via counteracting amyloid cytotoxicity."

Related Drugs and Biologics

1.	Antineoplastic Agents (Antineoplastics)
2.	acteoside
3.	Glycosides
4.	poliumoside
5.	Therapeutic Uses
6.	Xylenes (Xylene)
7.	Raffinose
8.	Polysaccharides (Glycans)
9.	Camptothecin
10.	Antioxidants