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endonuclease R

mammalian endonuclease that cleaves G.C rich DNA sequences; rescuing intact adeno-associated virus sequences

Also Known As:

Endo R

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Esterases: 1574
      - Deoxyribonucleases: 1259
        Endodeoxyribonucleases
        endonuclease R: 4
      - Endonucleases: 1227
        Endodeoxyribonucleases
        endonuclease R: 4

Experts

1.	Anur, Pavana: 1 article (10/2016)
2.	Brown, Myles: 1 article (10/2016)
3.	Creighton, Chad J: 1 article (10/2016)
4.	De Angelis, Carmine: 1 article (10/2016)
5.	Edwards, Dean P: 1 article (10/2016)
6.	Fu, Xiaoyong: 1 article (10/2016)
7.	Grasso, Catherine S: 1 article (10/2016)
8.	Gray, Joe W: 1 article (10/2016)
9.	Griffith, Obi L: 1 article (10/2016)
10.	Gutierrez, Carolina: 1 article (10/2016)

Related Diseases

1.	Wounds and Injuries (Trauma) 08/01/2012 - "This study investigated patients who sustained peripheral arterial trauma, presented with clinical signs of shock, and underwent urgent endovascular repair (endo-R). " 08/01/2012 - "Endo-R of traumatic non-aortic arterial injuries or spontaneous ruptures might be considered as a treatment option-in preference to open repair-even in emergency settings such as in shock patients. "
2.	Shock 08/01/2012 - "This study investigated patients who sustained peripheral arterial trauma, presented with clinical signs of shock, and underwent urgent endovascular repair (endo-R). " 08/01/2012 - "Endo-R of traumatic non-aortic arterial injuries or spontaneous ruptures might be considered as a treatment option-in preference to open repair-even in emergency settings such as in shock patients. "
3.	Infections 10/01/1975 - "Unique fragments of adenovirus type 2 DNA generated by cleavage with endonuclease R-Eco RI or endonuclease R-Hsu I (Hin dIII) were used to map cytoplasmic viral RNAs transcribed early in productive infection. " 04/01/1975 - "Cytoplasmic RNA, isolated from cells late after infection by adenovirus type 2 and fractionated by hybridization to specific fragments of adenovirus DNA produced by cleavage with the endonuclease R-EcoRI, was used as template for protein synthesis in cell-free mammalian extracts. "
4.	Spontaneous Rupture 08/01/2012 - "Endo-R of traumatic non-aortic arterial injuries or spontaneous ruptures might be considered as a treatment option-in preference to open repair-even in emergency settings such as in shock patients. "
5.	Breast Neoplasms (Breast Cancer) 10/25/2016 - "FOXA1 is gene-amplified and/or overexpressed in Endo-R derivatives of several breast cancer cell line models. " 10/25/2016 - "Here, we report preclinical evidence for a role of FOXA1 in Endo-R breast cancer as well as evidence for its clinical significance. " 10/25/2016 - "Forkhead box protein A1 (FOXA1) is a pioneer factor of estrogen receptor α (ER)-chromatin binding and function, yet its aberration in endocrine-resistant (Endo-R) breast cancer is unknown. "

Related Drugs and Biologics

1.	DNA (Deoxyribonucleic Acid)
2.	Forkhead Transcription Factors (Forkhead Box Proteins)
3.	Deoxyribonuclease EcoRI (Eco RI)
4.	RNA (Ribonucleic Acid)
5.	Estrogen Receptors
6.	Proteins (Proteins, Gene)
7.	Chromatin