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2-amino-4-methyl-5-phosphono-3-pentenoic acid

N-methyl-D-aspartate receptor antagonist; structure given in first source; RN given refers to cpd without isomeric designation; CGP-40116 is the (R)-enantiomer of CGP-37849; CGP-40017 is the L-isomer
Also Known As:
2-amino-4-methyl-5-phosphono-3-pentenoic acid, (E)-isomer; 2-amino-4-methyl-5-phosphono-3-pentenoic acid, E(+-)-isomer; 2-amino-4-methyl-5-phosphono-3-pentenoic acid, R-(E)-isomer; 2-amino-4-methyl-5-phosphono-3-pentenoic acid, S-(E)-isomer; 4-methyl-APPA; CGP 37849; CGP 40017; CGP 40116; CGP-37849; CGP-40017; CGP-40116; CGP40.116; 3-Pentenoic acid, 2-amino-4-methyl-5-phosphono-, (E)-(+-)-
Networked: 51 relevant articles (2 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Kleinrok, Z: 2 articles (10/2000 - 01/2000)
2. Rejdak, R: 2 articles (10/2000 - 01/2000)
3. Rejdak, K: 2 articles (10/2000 - 01/2000)
4. Sieklucka-Dziuba, M: 2 articles (10/2000 - 01/2000)
5. Czuczwar, S J: 2 articles (10/2000 - 01/2000)
6. Mares, Pavel: 1 article (05/2005)
7. Slamberová, Romana: 1 article (05/2005)
8. Czyrak, Anna: 1 article (09/2003)
9. Zajaczkowski, Wojciech: 1 article (09/2003)
10. Wedzony, Krzystof: 1 article (09/2003)

Related Diseases

1. Seizures (Seizure)
2. Status Epilepticus (Complex Partial Status Epilepticus)
3. Necrosis
4. Brain Ischemia (Cerebral Ischemia)
5. Anxiety Disorders (Anxiety Disorder)

Related Drugs and Biologics

1. N-Methylaspartate (NMDA)
2. Pilocarpine (Ocusert)
3. Glutamic Acid (Glutamate)
4. Valproic Acid (Valproate, Semisodium)
5. Lithium
6. Dizocilpine Maleate (Dizocilpine)
7. CGP 39551
8. Memantine (Namenda)
9. Haloperidol (Haldol)
10. 2-amino-4-methyl-5-phosphono-3-pentenoic acid

Related Therapies and Procedures

1. Oral Administration