|1.||Kure, Shigeo: 4 articles (04/2012 - 01/2005)|
|2.||Matsubara, Yoichi: 3 articles (04/2012 - 01/2005)|
|3.||Komatsuzaki, Shoko: 2 articles (04/2012 - 09/2008)|
|4.||Aoki, Yoko: 2 articles (04/2012 - 09/2008)|
|5.||Narisawa, Ayumi: 2 articles (04/2012 - 09/2008)|
|6.||Fujiwara, Kazuko: 2 articles (04/2012 - 09/2005)|
|7.||Kartal, Erkan: 1 article (05/2015)|
|8.||Mert, Gulen Gul: 1 article (05/2015)|
|9.||Yilmaz, Berna Seker: 1 article (05/2015)|
|10.||Mungan, Neslihan Onenli: 1 article (05/2015)|
11/01/2009 - "Nonketotic hyperglycinemia is an inborn error of metabolism caused by mutations in genes encoding protein in the mitochondrial glycine cleavage system. "
09/02/2005 - "Crystal structure of human T-protein of glycine cleavage system at 2.0 A resolution and its implication for understanding non-ketotic hyperglycinemia."
04/20/2005 - "Structure of P-protein of the glycine cleavage system: implications for nonketotic hyperglycinemia."
08/01/2002 - "Nonketotic hyperglycinemia is a life-threatening disorder in neonates characterized by a deficiency of the glycine cleavage system. "
01/01/2001 - "Chromosomal localization, structure, single-nucleotide polymorphisms, and expression of the human H-protein gene of the glycine cleavage system (GCSH), a candidate gene for nonketotic hyperglycinemia."
01/01/1982 - "These findings suggest that the reduction of the glycine cleavage system in the liver of ketotic hyperglycinemia occurs secondarily as speculated previously and is caused mainly by a decrease of H-protein activity."
01/01/1982 - "Glycine cleavage system in ketotic hyperglycinemia: a reduction of H-protein activity."
07/15/1988 - "Glycine decarboxylase, a constituent of the glycine cleavage system, in patients with either nonketotic or ketotic hyperglycinemia (NKH and KH) was examined using an anti-chicken glycine decarboxylase antibody. "
03/01/1997 - "Hyperglycinemia is a non rarely observed biochemical finding which can be caused by a primary defect of the glycine cleavage system (nonketotic hyperglycinemia) or by an enzymatic block due to toxic metabolites (ketotic hyperglycinemia in organic acidurias) or to specific drugs (such as sodium valproate). "
|3.||Neurologic Manifestations (Neurological Manifestations)
11/01/1981 - "Although no ill effects of cysteamine treatment were immediately apparent, patients receiving cysteamine should be monitored carefully for the appearance of any neurologic symptoms which might be referable to inhibition of the glycine cleavage system."
09/01/2008 - "Glycine encephalopathy (GE) is caused by an inherited deficiency of the glycine cleavage system (GCS) and characterized by accumulation of glycine in body fluids and various neurologic symptoms. "
04/16/2015 - "Thus, SHMT2 is required for cancer cells to adapt to the tumour environment, but also renders these cells sensitive to glycine cleavage system inhibition. "
02/01/2012 - "Analyses of tumor tissue extracts showed single- and multiple-label incorporation from [2-(13)C]-glycine into serine from metabolism through the serine hydroxymethyltransferase and glycine cleavage system pathways. "
|5.||Metabolic Diseases (Metabolic Disease)
10/01/2011 - "Glycine encephalopathy (GE), also known as non-ketotic hyperglycinemia, is a life-threatening metabolic disease caused by inherited deficiency of the glycine cleavage system (GCS). "
06/01/2005 - "Glycine encephalopathy is a rare autosomal recessive metabolic disease characterized by glycine accumulation in body fluids owing to a defect in the glycine cleavage system. "
|1.||Glycine Dehydrogenase (Decarboxylating)
|3.||Complementary DNA (cDNA)
|4.||Glycine (Aminoacetic Acid)
|7.||Glycine Hydroxymethyltransferase (Serine Hydroxymethyltransferase)
|8.||Proteins (Proteins, Gene)
|10.||Aminomethyltransferase (Glycine Synthase)