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O,O'- dimethyl- O- (6- chlorobicyclo(3.2.0)heptadiene- 1,5- yl)phosphate

Chostaquick
Also Known As:
DCHP
Networked: 4 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Shu, Weiqun: 1 article (01/2014)
2. Qiu, Zhiqun: 1 article (01/2014)
3. Wang, Yanzhou: 1 article (01/2014)
4. Garcia, Jose M: 1 article (01/2014)
5. Li, Junnan: 1 article (01/2014)
6. Tan, Yao: 1 article (01/2014)
7. Luo, Jiaohua: 1 article (01/2014)
8. Wang, Lingqiao: 1 article (01/2014)
9. Huang, Yujing: 1 article (01/2014)
10. Lin, Hui: 1 article (01/2014)

Related Diseases

1. Fetal Weight
2. Fetal Growth Retardation (Intrauterine Growth Retardation)
3. Hypertrophy
4. Body Weight (Weight, Body)
12/01/2005 - "With regard to effects on the offspring, inhibition of body weight gain was found in the F1 and F2 6000 ppm, and decrease of anogenital distance (AGD) and appearance of areola mammae were observed in the F1 male 6000 ppm and F2 male receiving doses of 1200 ppm or 6000 ppm. No effects of DCHP treatment on the offspring were observed on results of clinical signs, the number of the pups delivered, sex ratio, viability, physical development, reflex and response tests, external abnormalities, organ weights, or necropsy findings. "
08/01/2009 - "Maternal food consumption and body weight gain were significantly reduced at 750 mg kg(-1) per day of DnHP and at the two high doses of DCHP. "
12/01/2005 - "The reproductive toxicity of dicyclohexyl phthalate (DCHP) was evaluated in a two generation test in which male and female Sprague-Dawley (SD) rats of parental (F0) and F1 generation were exposed to DCHP in the diet at concentrations of 0 (control), 240, 1200 or 6000 ppm. With regard to the effects on the F0 and F1 parental animals, changes included inhibition of body weight gain and food consumption, diffuse hypertrophy of hepatocytes, and hypertrophy of thyroidal follicular epithelial cells at the doses of 1200 ppm and 6000 ppm. The following changes were observed in the 6000 ppm group: increase weights of the liver and thyroid, increased hyaline droplets in the renal proximal tubular epithelium (F0 and F1 males), reduction of prostatic weight (F1 males), and diffuse and/or focal atrophy of testicular seminiferous tubules (F1 males). "
5. Cryptorchidism (Undescended Testes)

Related Drugs and Biologics

1. N,N-dinitrosohomopiperazine
2. Diethylhexyl Phthalate (DEHP)
3. 4-boronic acid benzophenone
4. dicyclohexyl phthalate
5. 1-(2-(dodecyloxy)ethyl)pyrrolidine hydrochloride (DEP)