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KDEL receptor

integral membrane protein which binds proteins which contain Lys-Asp-Glu-Leu on their carboxy terminus

Also Known As:

KDEL receptors; receptor, KDEL

Networked: 11 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Cell Surface Receptors: 2125
      - Peptide Receptors: 1159
        KDEL receptor: 11

Experts

1.	Aoe, Tomohiko: 2 articles (01/2014 - 09/2004)
2.	Koseki, Haruhiko: 2 articles (01/2014 - 09/2004)
3.	Mimura, Naoya: 2 articles (01/2014 - 09/2004)
4.	Carlos, Anthony J: 1 article (06/2021)
5.	Ha, Dat P: 1 article (06/2021)
6.	Lee, Amy S: 1 article (06/2021)
7.	Tsai, Yuan-Li: 1 article (06/2021)
8.	Van Krieken, Richard: 1 article (06/2021)
9.	Campos de Carvalho, Antônio Carlos: 1 article (01/2021)
10.	Christie, Michelle Lopes Araújo: 1 article (01/2021)

Related Diseases

1.	Neurodegenerative Diseases (Neurodegenerative Disease) 01/01/2014 - "The defect in retrieval of BiP by the KDEL receptor leads to impaired activities in quality control and autophagy, suggesting that functional defects in the ER chaperones may contribute to the late onset of neurodegenerative diseases. " 09/08/2011 - "The KDEL receptor induces autophagy to promote the clearance of neurodegenerative disease-related proteins."
2.	Inflammation (Inflammations) 05/23/2023 - "Further mechanistic studies indicated that SAA upregulates the expression of lncRNA NR2F2-AS1, which reverses the abnormal localization of the KDEL receptor (KDELR) caused by inflammation. "
3.	Vesicular Stomatitis 09/12/2000 - "We report immunoelectron microscopy experiments establishing that a Golgi-restricted SNARE, GOS 28, is present in the same population of COPI vesicles as anterograde cargo marked by vesicular stomatitis virus glycoprotein, but is excluded from the COPI vesicles containing retrograde-targeted cargo (marked by KDEL receptor). " 02/01/1999 - "Colabeling experiments for Sec22b/ERS-24 with Golgi mannosidase II, the KDEL receptor, and the envelope glycoprotein G (VSVG) of vesicular stomatitis virus (VSV) en route from the ER to the Golgi under normal, brefeldin A, or nocodazole-treated cells suggest that Sec22b/ERS-24 is enriched in the pre-Golgi intermediate compartment (IC). "
4.	Carcinogenesis 07/01/2020 - "The KDEL receptor is a seven-transmembrane-domain protein, which plays a key role in ER quality control and in the ER stress response, KDELR2 involved in regulation of cellular functions, including cell proliferation, survival, promotes glioblastoma tumorigenesis. "
5.	Myocardial Ischemia (Ischemic Heart Diseases) 01/01/2021 - "New Cardiomyokine Reduces Myocardial Ischemia/Reperfusion Injury by PI3K-AKT Pathway Via a Putative KDEL-Receptor Binding."

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Long Noncoding RNA
3.	Coat Protein Complex I (COPI)
4.	Glycoproteins (Glycoprotein)
5.	Brefeldin A
6.	GTP-Binding Proteins (G-Protein)
7.	Nocodazole
8.	Propranolol (Inderal)
9.	mannosyl-oligosaccharide 1,3 - 1,6-alpha-mannosidase