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dimethyldioxirane

structure given in first source; powerful oxidizing agent

Also Known As:

3,3-dimethyldioxirane; DMDO; dioxirane, 3,3-dimethyl-

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Ethers: 242
  - Cyclic Ethers: 12
    - Epoxy Compounds: 689
      - dimethyldioxirane: 7

Experts

1.	Biz, Carlo: 2 articles (09/2020 - 01/2018)
2.	Ruggieri, Pietro: 2 articles (09/2020 - 01/2018)
3.	Di Domenico, Francesca: 1 article (12/2020)
4.	Ingham, Neil J: 1 article (12/2020)
5.	Lewis, Morag A: 1 article (12/2020)
6.	Prosser, Haydn M: 1 article (12/2020)
7.	Steel, Karen P: 1 article (12/2020)
8.	Corradin, Marco: 1 article (01/2018)
9.	Dalmau-Pastor, Miki: 1 article (01/2018)
10.	Gastaldo, Stefano: 1 article (01/2018)

Related Diseases

1.	Diabetic Foot 09/01/2020 - "Minimally invasive distal metatarsal diaphyseal osteotomy (DMDO) is an effective procedure for the treatment of complicated chronic diabetic foot ulcers under the heads of all lateral metatarsal bones (including the fifth). " 01/01/2018 - "Minimally Invasive Distal Metatarsal Diaphyseal Osteotomy (DMDO) for Chronic Plantar Diabetic Foot Ulcers."
2.	Ulcer 09/01/2020 - "Minimally invasive distal metatarsal diaphyseal osteotomy (DMDO) is an effective procedure for the treatment of complicated chronic diabetic foot ulcers under the heads of all lateral metatarsal bones (including the fifth). " 01/01/2018 - "Minimally Invasive Distal Metatarsal Diaphyseal Osteotomy (DMDO) for Chronic Plantar Diabetic Foot Ulcers."
3.	Dehydration (Water Stress) 04/27/2011 - "DMDO oxidation of functionalized α-diazo-β-ketoacetates, formed by zinc triflate catalyzed Mukaiyama-aldol condensation of methyl diazoacetoacetate with aldehydes, occurred in quantitative yield to form dihydrofuranols that undergo acid catalyzed dehydration under mild conditions to generate 3-methoxyfuran-2-carboxylates in good yield." 06/26/2003 - "Dimethyldioxirane (DMDO) C-H oxidation of ketone 17 to hemiketal 18 (82%), bis-dehydration to vinyl ether 21 (77%), and DMDO again provides C-23 axial alcohol 23 (99%). "
4.	Carcinogenesis 06/01/1998 - "It was found recently that 17beta-estradiol (E2) could be activated by the epoxide-forming oxidant dimethyldioxirane (DMDO) resulting in the inhibition of rat liver nuclear and nucleolar RNA synthesis in vitro (Carcinogenesis, 17, 1957-1961, 1996). "
5.	Hearing Loss (Hearing Impairment) 12/14/2020 - "This suggests the more severe phenotype of Mir96 Dmdo mutants compared with Mir183/96 mutants, including progressive hearing loss in Mir96 Dmdo heterozygotes, is likely to be mediated by the gain of novel target genes in addition to the loss of its normal targets. "

Related Drugs and Biologics

1.	dimethyldioxirane
2.	Oxidants (Oxidizing Agents)
3.	RNA (Ribonucleic Acid)
4.	Ketones
5.	Epoxy Compounds (Epoxides)
6.	Aldehydes
7.	Acids
8.	anethole oxide
9.	3-hydroxybutanal (aldol)
10.	vinyl ether (divinyl ether)

Related Therapies and Procedures

1.	Osteotomy