HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

columbianadin

furanocoumarin isolated from Peucedanum palustre; RN given refers to columbianadin, (S-(Z))-isomer

Networked: 9 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Coumarins: 826
        columbianadin: 9
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Coumarins: 826
        columbianadin: 9

Experts

1.	Choi, Jae Sue: 2 articles (05/2016 - 09/2014)
2.	Lee, Sang Kook: 2 articles (05/2016 - 09/2014)
3.	Hou, Shaw-Min: 1 article (05/2020)
4.	Hsia, Chih-Hsuan: 1 article (05/2020)
5.	Hsia, Chih-Wei: 1 article (05/2020)
6.	Jayakumar, Thanasekaran: 1 article (05/2020)
7.	Sheu, Joen-Rong: 1 article (05/2020)
8.	Tsai, Cheng-Lin: 1 article (05/2020)
9.	Velusamy, Marappan: 1 article (05/2020)
10.	Dong, Bing: 1 article (02/2019)

Related Diseases

1.	Pneumonia (Pneumonitis) 09/11/2014 - "Moreover, columbianadin was also proved to possess significant inhibitory activity against LPS-induced lung inflammation following oral administration at a dose of 20-60 mg/kg. The roots of Angelica decursiva were proved to be effective in the treatment of lung inflammation. " 09/11/2014 - "Water and 70% ethanol extracts of the roots of Angelica decursiva showed considerable inhibitory activity against LPS-induced lung inflammation in mice following oral administration at a dose of 400 mg/kg. Five coumarin derivatives including columbianadin, umbelliferone, umbelliferone 6-carboxylic acid, nodakenin and nodakenetin were isolated. "
2.	Pain (Aches) 01/01/2019 - "A previous study has reported that columbianadin (CBN), a major coumarin in RAP inhibits acute and inflammatory pain behaviors. " 01/04/2017 - "This results demonstrate that CRAP possess remarkable antinociceptive activities which may be due to osthole and columbianadin at least in part, supporting the folkloric usage of the plant to treat various pain diseases."
3.	Inflammation (Inflammations) 09/11/2014 - "Inhibition of airway inflammation by the roots of Angelica decursiva and its constituent, columbianadin." 02/02/2019 - "Columbianadin Suppresses Lipopolysaccharide (LPS)-Induced Inflammation and Apoptosis through the NOD1 Pathway." 11/15/2023 - "Therapeutic effects of columbianadin from Angelicae Pubescentis radix on the progression of collagen-induced rheumatoid arthritis by regulating inflammation and oxidative stress."
4.	Thrombosis (Thrombus) 05/06/2020 - "Modulation of human platelet activation and in vivo vascular thrombosis by columbianadin: regulation by integrin αIIbβ3 inside-out but not outside-in signals."
5.	Rheumatic Diseases (Rheumatism) 01/01/2014 - "Columbianadin, one of the active coumarins, is isolated from Radix Angelicae pubescentis which has been used as a traditional Chinese medicine for the treatment of rheumatic diseases for thousands of years. "

Related Drugs and Biologics

1.	coumarin
2.	Coumarins
3.	7-hydroxycoumarin (umbelliferone)
4.	Therapeutic Uses
5.	Integrins
6.	Lipopolysaccharides
7.	Esculin (Aesculin)
8.	Collagen
9.	Calcium
10.	Ethanol (Ethyl Alcohol)

Related Therapies and Procedures

1.	Oral Administration
2.	Chinese Traditional Medicine (Traditional Chinese Medicine)