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4-dimethylcaffeoylmussatioside

phenylpropanoid from liana Mussatia; structure given in first source

Also Known As:

MeCM

Networked: 10 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Polysaccharides: 15383
  - Oligosaccharides: 3566
    - Trisaccharides: 123
      - 4-dimethylcaffeoylmussatioside: 10
- Glycosides: 2119
  - 4-dimethylcaffeoylmussatioside: 10
Organic Chemicals: 133
- Carboxylic Acids: 973
  - Carbocyclic Acids
    - Phenylpropionates
      - 4-dimethylcaffeoylmussatioside: 10

Experts

1.	Lin, Hang: 2 articles (01/2022 - 12/2019)
2.	Alexander, Peter G: 1 article (01/2022)
3.	Clark, Karen L: 1 article (01/2022)
4.	Di, Jun: 1 article (01/2022)
5.	Gao, Xian: 1 article (01/2022)
6.	Guo, Junfei: 1 article (01/2022)
7.	Hines, Sophie: 1 article (01/2022)
8.	Hou, Zhiyong: 1 article (01/2022)
9.	Shang, Jiangyinzi: 1 article (01/2022)
10.	Tan, Susheng: 1 article (01/2022)

Related Diseases

1.	Neuralgia (Stump Neuralgia) 08/25/2015 - "MECM administered orally at the doses of 250 and 500 mg/kg, induced long lasting and significant antihyperalgesic effects on CFA-inflammatory and PSNL-induced neuropathic pain. " 08/25/2015 - "The present results demonstrate that the oral administration of MECM to mice resulted in long lasting antihyperalgesic activity in inflammatory and neuropathic pain as well as in acute and persistent pain. " 08/25/2015 - "The present study evaluates the antinociceptive properties of the methanol/methylene chloride extract (MECM) of the stem bark of this plant using mice models of persistent inflammatory and neuropathic pain, and assesses its mechanism of action. " 08/25/2015 - "MECM was tested on Complete Freund adjuvant (CFA)-induced persistent thermal and mechanical pain, neuropathic pain induced by partial sciatic nerve ligation (PSNL), prostaglandin E2 (PGE2)-induced acute mechanical hyperalgesia, as well as on nociception induced by capsaicin in mice. "
2.	Pain (Aches) 09/01/2014 - "In the formalin test, the index of pain inhibition of early and late phases was, respectively, 47.83 and 81.98% for MeAB, 56.10 and 63.81% for MeCM, and 42.84 and 63.29% for MeCT (200 mg/kg). " 08/25/2015 - "The present results demonstrate that the oral administration of MECM to mice resulted in long lasting antihyperalgesic activity in inflammatory and neuropathic pain as well as in acute and persistent pain. " 08/25/2015 - "The mechanism of action of MECM was evaluated by using glibenclamide on PGE2-induced hyperalgesia or rimonabant on capsaicin-induced pain. " 08/25/2015 - "MECM was tested on Complete Freund adjuvant (CFA)-induced persistent thermal and mechanical pain, neuropathic pain induced by partial sciatic nerve ligation (PSNL), prostaglandin E2 (PGE2)-induced acute mechanical hyperalgesia, as well as on nociception induced by capsaicin in mice. "
3.	Hypertrophy 01/01/2022 - "Previously, we developed a method to induce hMSC chondrogenesis within self-generated extracellular matrix (mECM), which formed a cartilage tissue with a lower hypertrophy level than conventional hMSC pellets. " 12/01/2019 - "In comparison to conventional pellet culture, chondrogenically induced MSC-mECM displays a similar level of chondrogenesis, but with significantly reduced hypertrophy. "
4.	Osteophyte 12/01/2020 - "When applied to an orthotopic model of meniscal injury in SD rat, mECM is superior than collagen I scaffold in reduction of osteophyte formation and prevention of joint space narrowing and osteoarthritis development as evidenced by histology and micro-CT analysis. "
5.	Teratoma (Teratoid Tumor) 10/01/2017 - "mECM preparations also completely inhibited teratoma formation from ESC inoculations. "

Related Drugs and Biologics

1.	Methanol (Carbinol)
2.	Methylene Chloride (Dichloromethane)
3.	Hydrogels
4.	Dinoprostone (PGE2)
5.	Testosterone (Sustanon)
6.	Glyburide (Glibenclamide)
7.	Freund's Adjuvant
8.	Formaldehyde (Formol)
9.	Collagen
10.	Carrageenan

Related Therapies and Procedures

1.	Ligation
2.	Oral Administration