kei-kyoh-zoh-soh-oh-shin-bu-toh

01/01/1990 - "The present results demonstrate the antinociceptive action of TJ-8023, and suggest that it is more effective in easing a hyperalgesia in morbid state than in suppressing a nociception in the normal one."
01/01/1990 - "Such a hyperalgesia was reversed by a single (30 and 100 mg/kg) or repeated administration (100 and 300 mg.kg-1.d-1) of TJ-8023. "
01/01/1990 - "TJ-8023 (100 mg.kg-1.d-1) inhibited the induction of adjuvant-induced hyperalgesia of rats in the paw-pressure test following prophylactic administration, and normalized the nociceptive threshold at a dose of 600 mg.kg-1.d-1, without effects on adjuvant-induced inflammation. "
01/01/2019 - "Prophylactic Repetitive Treatment with the Herbal Medicine Kei-kyoh-zoh-soh-oh-shin-bu-toh Attenuates Oxaliplatin-Induced Mechanical Allodynia by Decreasing Spinal Astrocytes."
01/01/2019 - "In this study, we examined whether the traditional herbal formulation Kei-kyoh-zoh-soh-oh-shin-bu-toh (KSOT) could relieve the mechanical allodynia induced by chemotherapeutic drugs (oxaliplatin, paclitaxel, vincristine, and bortezomib) in mice. "

01/01/1990 - "TJ-8023 (100 mg.kg-1.d-1) inhibited the induction of adjuvant-induced hyperalgesia of rats in the paw-pressure test following prophylactic administration, and normalized the nociceptive threshold at a dose of 600 mg.kg-1.d-1, without effects on adjuvant-induced inflammation. "