|1.||Abrams, Scott I: 8 articles (06/2015 - 06/2003)|
|2.||Gabriele, Lucia: 5 articles (10/2014 - 12/2012)|
|3.||Mattei, Fabrizio: 5 articles (10/2014 - 12/2012)|
|4.||Schiavoni, Giovanna: 5 articles (10/2014 - 12/2012)|
|5.||Ozato, Keiko: 5 articles (02/2014 - 11/2003)|
|6.||Belardelli, Filippo: 4 articles (10/2014 - 12/2012)|
|7.||Tamura, Tomohiko: 4 articles (01/2014 - 11/2003)|
|8.||Liu, Kebin: 4 articles (10/2013 - 06/2003)|
|9.||Eklund, Elizabeth A: 4 articles (03/2012 - 09/2006)|
|10.||Levi, Ben-Zion: 4 articles (04/2011 - 11/2003)|
|1.||Pancreatic Neoplasms (Pancreatic Cancer)
|2.||Listeriosis (Listeria Infection)
06/20/2015 - "Interferon regulatory factor-8 (IRF8), originally identified as a leukemic tumor suppressor, can also exert anti-neoplastic activities in solid tumors. "
11/28/2014 - "Interferon regulatory factor 8 (IRF8), as a central element of IFN-γ-signaling, plays a critical role in tumor suppression. "
01/01/2012 - "Therefore, in our preclinical tumor model, we tested the hypothesis that IRF-8 expression is important for response to HDACi-based antitumor activity. "
01/01/2012 - "Furthermore, we and others have shown that epigenetic mechanisms are involved in repression of IRF-8 in tumors. "
10/14/2010 - "Combined losses of IRF-4 and IRF-8 therefore can cooperate in the development of both myeloid and lymphoid tumors."
12/01/2013 - "Furthermore, infection neither inhibits LPS-induced MAPK or NFκB activation nor blocks IFN-γ-activated IRF-1 and IRF-8. "
12/01/2013 - "major infection does not elicit significant NFκB p65, MAPK, IRF-1 or IRF-8 activation in WT or CD11b-deficient macrophages. "
02/01/2008 - "Thus, interplay between repression and activation state of the Nramp1 promoter mediated by IRF-8 provides the molecular basis by which macrophages resist intraphagosomal pathogens at early stage after infection."
03/01/2002 - "IFN-gamma is a key cytokine controlling Brucella infection, and the diverse functions of this cytokine are mediated by IFN regulatory factors (IRFs) such as IRF-1, IRF-2, and IFN consensus sequence binding protein (ICSBP). "
01/01/2013 - "In this study, IRF-8 deficient mice (IRF-8⁻/⁻) were aerogenously infected with a low-dose Mtb Erdman virulent strain and the course of infection was compared with that induced in wild-type (WT-B6) counterparts. "
|5.||BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
07/01/2012 - "We used mice deficient in interferon regulatory factor 8 (IRF8(-/-)) in hematopoietic cells that develop a chronic myelogenous leukemia-like phenotype. "
10/14/2010 - "We found that mice deficient in both IRF-4 and IRF-8 develop from a very early age a more aggressive chronic myelogenous leukemia-like disease than mice deficient in IRF-8 alone, correlating with a greater expansion of granulocyte-monocyte progenitors. "
10/14/2010 - "The closely related family member IRF-8 is a critical regulator of myelopoiesis, which when deleted in mice results in a syndrome highly similar to human chronic myelogenous leukemia. "
06/01/2001 - "Mice deficient in the interferon consensus sequence binding protein (ICSBP) develop a disease resembling chronic myeloid leukemia (CML), which in humans is caused by the BCR/ABL oncoprotein. "
11/01/2007 - "The loss of IRF-8 in myeloid cells results in a chronic myelogenous leukemia-like syndrome, suggesting that IRF-8 behaves as a tumor suppressor gene in certain hematopoietic malignancies. "
|2.||Interferon Regulatory Factor-1 (Interferon Regulatory Factor 1)
|3.||Nitric Oxide (Nitrogen Monoxide)
|4.||Interferon-gamma (Interferon, gamma)
|5.||Staphylococcal Protein A (A, Protein)
|6.||butyl 3-(1H-tetrazol-5-yl)oxanilate (MTB)
|7.||Transcription Factors (Transcription Factor)
|8.||Interleukin-12 (IL 12)
|9.||interferon regulatory factor-8 (interferon consensus sequence binding protein)