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2- ((3- chloroethyl)- 3- nitrosoureido)glucopyranose
Also Known As:
CHLZ
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Amides: 2428
Urea: 15015
Nitrosourea Compounds: 21
2-((3-chloroethyl)-3-nitrosoureido)glucopyranose: 2
Nitroso Compounds: 446
Nitrosourea Compounds: 21
2-((3-chloroethyl)-3-nitrosoureido)glucopyranose: 2
Related Diseases
1.
Sarcoma (Soft Tissue Sarcoma)
06/01/1982 - "
transplanted KHT sarcomas were treated with varying doses of either 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) or 2-[3-(2-chloroethyl)-3-nitrosoureido]-D-glucopyranose (chlorozotocin; CHLZ) as single agents or in combination with 1 mg/g of the chemical radiosensitizer, misonidazole (MISO).
"
2.
Neoplasms (Cancer)
10/01/1985 - "
Early (2-4) passage cultures from these tumors were treated in vitro with model drugs for alkylation (BCNU, CHLZ (2-[3-(2-chloroethyl)-3-nitrosoureido]-2-deoxy-D-glucopyranose), ENU (N-ethyl-N-nitrosourea), cross-linking (BCNU, CHLZ) and carbamoylation BHCNU (1,3 bis (trans-4-hydrocyclohexyl)-1-nitrosourea): dose-schedules were compatible with clinically achievable levels.
"
Related Drugs and Biologics
1.
Carmustine (FIVB)
2.
Misonidazole
3.
Ethylnitrosourea (N-Ethyl-N-nitrosourea)
4.
N,N'- bis(4- hydroxycyclohexyl)- N'- nitrosourea
5.
chlorozotocin