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tyrosinase-related protein-1

converts 5,6-dihydroxyindole-2-carboxylic acid to melanochrome in premelanosomes; shares 40% amino acid homology with sequence of mouse tyrosinase; has no tyrosinase activity; amino acid sequence in first source; melanocyte-specific promoter; do not confuse with trophoblast protein, also known as TRP-1; see also C079621 and C489799
Also Known As:
5,6-dihydroxyindole-2-carboxylic acid oxidase; TRP-1 protein, tyrosinase-related; TRP1 protein, tyrosinase-related; dihydroxyindole-carboxylic acid oxidase
Networked: 34 relevant articles (1 outcomes, 4 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Houghton, Alan N: 3 articles (12/2008 - 06/2002)
2. Guevara-Patiño, José A: 2 articles (12/2011 - 05/2006)
3. Merghoub, Taha: 2 articles (12/2008 - 05/2006)
4. Wolchok, Jedd D: 2 articles (12/2008 - 05/2006)
5. Rizzuto, Gabrielle: 2 articles (12/2008 - 05/2006)
6. Restifo, Nicholas P: 2 articles (12/2008 - 01/2003)
7. Saliou, Claude: 1 article (01/2014)
8. Koga, Shihiro: 1 article (01/2014)
9. Nagata, Takeshi: 1 article (01/2014)
10. Hu, Yaping: 1 article (01/2014)

Related Diseases

1. Melanoma (Melanoma, Malignant)
2. Neoplasms (Cancer)
3. Vitiligo
4. Sarcoma (Soft Tissue Sarcoma)
5. Oculocutaneous Albinism (Albinism, Yellow Mutant)

Related Drugs and Biologics

1. DNA Vaccines
2. Monophenol Monooxygenase (Tyrosinase)
3. dopachrome isomerase
4. Proteins (Proteins, Gene)
5. Microphthalmia-Associated Transcription Factor
6. Complementary DNA (cDNA)
7. trophoblastin
8. Antibodies
9. Type 1 Melanocortin Receptor
10. Endothelin-3 (Endothelin 3)