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bilobol

structure given in first source; RN given refers to (Z)-isomer; RN for cpd without isomeric designation not avail 6/90

Also Known As:

5-(8-pentadecenyl)-1,3-benzenediol

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Phenols: 677
        Resorcinols: 4
        bilobol: 3

Experts

1.	Chen, Min: 1 article (08/2015)
2.	Chen, Yongchang: 1 article (08/2015)
3.	Li, Yueying: 1 article (08/2015)
4.	Liu, Yali: 1 article (08/2015)
5.	Xu, Jin: 1 article (08/2015)
6.	Yang, Xiaoming: 1 article (08/2015)

Related Diseases

1.	Inflammation (Inflammations) 08/01/2015 - "By performing an ELISA, it was observed that bilobol was able to suppress the inflammation induced by LPS. " 08/01/2015 - "In the present study, HepG2 cells were treated with lipopolysaccharide (LPS), to induce inflammation, and/or bilobol. " 02/01/1990 - "Treatment with either 10 or 50 micrograms bilobol twice a week for 30 weeks did not result in any tumor development, thus suggesting that bilobol is not a complete promoter of skin carcinogenesis, despite generation of inflammation."
2.	Hepatocellular Carcinoma (Hepatoma) 08/01/2015 - "The present study aimed to demonstrate the anticarcinogenic action of bilobol against hepatocellular carcinoma, in order to lay the foundations for subsequent research into the mechanisms underlying its anticancer effects. " 08/01/2015 - "Bilobol inhibits the lipopolysaccharide-induced expression and distribution of RhoA in HepG2 human hepatocellular carcinoma cells."
3.	Neoplasms (Cancer) 02/01/1990 - "A comparative investigation of morphological changes induced by bilobol and TPA induced in the skin of CD-1 mice, and an assessment of the skin tumor promoting potential of bilobol were therefore performed. " 02/01/1990 - "Comparison of the effects of bilobol and 12-O-tetradecanoylphorbol-13-acetate on skin, and test of tumor promoting potential of bilobol in CD-1 mice." 08/01/2023 - "Furthermore, bioactivities such as anti-tumor activity and so on have been demonstrated for ginkgols, and bilobols, providing theoretical justification for ginkgols and bilobol as raw material for nutraceuticals, functional foods, pharmaceuticals, and cosmeceuticals. " 02/01/1990 - "Treatment with either 10 or 50 micrograms bilobol twice a week for 30 weeks did not result in any tumor development, thus suggesting that bilobol is not a complete promoter of skin carcinogenesis, despite generation of inflammation."
4.	Carcinogenesis 02/01/1990 - "Treatment with either 10 or 50 micrograms bilobol twice a week for 30 weeks did not result in any tumor development, thus suggesting that bilobol is not a complete promoter of skin carcinogenesis, despite generation of inflammation." 02/01/1990 - "The dose of 2.5 micrograms of TPA, which is usually used as tumor promoter in skin carcinogenesis, was equivalent to 50 micrograms of bilobol in irritant effect. "

Related Drugs and Biologics

1.	Lipopolysaccharides
2.	Irritants (Vesicants)
3.	Carcinogens
4.	Cosmeceuticals