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lentiginosine

from Astragalus lentiginosus

Also Known As:

1,2-di-epi-lentiginosine; 1,2-dihydroxyindolizidine; 1,2-Indolizinediol, octahydro-, (1S-(1alpha,2beta,8aalpha))-

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Alkaloids: 5398
  - lentiginosine: 3

Experts

1.	Brandi, Alberto: 2 articles (01/2014 - 05/2010)
2.	Cordero, Franca M: 2 articles (01/2014 - 05/2010)
3.	Giomi, Donatella: 1 article (01/2014)
4.	Cardona, Francesca: 1 article (05/2010)
5.	Grelli, Sandro: 1 article (05/2010)
6.	Macchi, Beatrice: 1 article (05/2010)
7.	Mastino, Antonio: 1 article (05/2010)
8.	Minutolo, Antonella: 1 article (05/2010)
9.	Chen, Wen: 1 article (11/2007)
10.	Huang, Pei-Qiang: 1 article (11/2007)

Related Diseases

1.

Neoplasms (Cancer)

01/01/2014 - "The non-natural enantiomer, (-)-lentiginosine, induces apoptosis on tumor cells of different origin and is poorly cytotoxic towards non-transformed cells. "
05/01/2010 - "D-(-)-Lentiginosine [(-)-4], the nonnatural enantiomer of the iminosugar indolizidine alkaloid L-(+)-lentiginosine, acts as apoptosis inducer on tumor cells of different origin, in contrast to its natural enantiomer. "
11/08/2007 - "Spiroketals and the corresponding aza-spiroketals are the structural features found in a number of bioactive natural products, and in compounds possessing photochromic properties for use in the area of photochemical erasable memory, self-development photography, actinometry, displays, filters, lenses of variable optical density, and photomechanical biomaterials etc. And (1R,8aS)-1-hydroxyindolizidine (3) has been postulated to be a biosynthetic precursor of hydroxylated indolizidines such as (+)-lentiginosine 1, (-)-2-epilentiginosine 2 and (-)-swainsonine, which are potentially useful antimetastasis drugs for the treatment of cancer. "

Related Drugs and Biologics

1.	Indolizidines
2.	Swainsonine
3.	Biocompatible Materials (Biomaterials)
4.	Alkaloids

Related Therapies and Procedures

1.	Lenses