Type 2 Diabetes Mellitus

A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.

Also Known As:

MODY; Noninsulin Dependent Diabetes Mellitus; Diabetes Mellitus, Type II; NIDDM; Diabetes Mellitus, Type 2; Diabetes Mellitus, Non Insulin Dependent; Diabetes Mellitus, Noninsulin Dependent; Diabetes Mellitus, Noninsulin-Dependent; Maturity-Onset Diabetes; Noninsulin-Dependent Diabetes Mellitus; Type 2 Diabetes; Adult-Onset Diabetes Mellitus; Diabetes Mellitus, Adult Onset; Diabetes Mellitus, Ketosis Resistant; Diabetes Mellitus, Maturity Onset; Diabetes Mellitus, Slow Onset; Diabetes, Maturity-Onset; Diabetes, Type 2; Ketosis-Resistant Diabetes Mellitus; Maturity Onset Diabetes; Maturity Onset Diabetes Mellitus; Non-Insulin-Dependent Diabetes Mellitus; Slow-Onset Diabetes Mellitus; Stable Diabetes Mellitus; Diabetes Mellitus, Adult-Onset; Diabetes Mellitus, Ketosis-Resistant; Diabetes Mellitus, Maturity-Onset; Diabetes Mellitus, Non-Insulin-Dependent; Diabetes Mellitus, Slow-Onset; Diabetes Mellitus, Stable; Maturity-Onset Diabetes Mellitus

Nutritional and Metabolic Diseases: 15
- Metabolic Diseases: 10142
  - Glucose Metabolism Disorders: 375
    - Diabetes Mellitus: 56563
      - Type 2 Diabetes Mellitus: 95492
Endocrine System Diseases: 968
- Diabetes Mellitus: 56563
  - Type 2 Diabetes Mellitus: 95492

1.	Type 2 Diabetes Mellitus (MODY) 05/01/1990 - "The best analogue, 5-(2-naphthalenylsulfonyl)-2,4-thiazolidinedione (AY-31,637) was equipotent to ciglitazone in two animal models of NIDDM."

5- (2- naphthalenylsulfonyl)- 2,4- thiazolidinedione

Bio-Agent Context: Research Results

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