Globosides

Glycosphingolipids containing N-acetylglucosamine (paragloboside) or N-acetylgalactosamine (globoside). Globoside is the P antigen on erythrocytes and paragloboside is an intermediate in the biosynthesis of erythrocyte blood group ABH and P 1 glycosphingolipid antigens. The accumulation of globoside in tissue, due to a defect in hexosaminidases A and B, is the cause of Sandhoff disease.

Also Known As:

Lactoneotetraosylceramide; Lacto N neotetraosylceramide; Lacto N tetraosylceramide; Cytolipins; Lacto-N-neotetraosylceramide; Lacto-N-tetraosylceramide

Organic Chemicals: 133
- Amides: 2428
  - Ceramides: 4082
    - Globosides: 13
Carbohydrates: 22023
- Glycoconjugates: 1353
  - Glycolipids: 2799
    - Glycosphingolipids: 1659
      - Neutral Glycosphingolipids: 101
        Ceramides: 4082
        Globosides: 13
Lipids: 114793
- Glycolipids: 2799
  - Glycosphingolipids: 1659
    - Neutral Glycosphingolipids: 101
      - Ceramides: 4082
        Globosides: 13
- Membrane Lipids: 1591
  - Sphingolipids: 3208
    - Glycosphingolipids: 1659
      - Neutral Glycosphingolipids: 101
        Ceramides: 4082
        Globosides: 13

O-acetyldisialosyl paragloboside

Bio-Agent Context: Research Results