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romazarit

Also Known As:

2-((2-(4-chlorophenyl)-4-methyl-5-oxazolyl)methoxy)-2-methylpropionic acid; Ro 31-3948; Ro-31-3948

Networked: 4 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Oxazoles: 89
      - romazarit: 4

Related Diseases

1.	Rheumatoid Arthritis 03/01/1995 - "1. The response to romazarit, a disease modifying anti-rheumatoid agent, was observed in patients with rheumatoid arthritis (RA) in a double-blind placebo controlled study. " 03/01/1992 - "A pharmacokinetic and tolerance study of romazarit in patients with rheumatoid arthritis." 03/01/1992 - "Romazarit is a new drug for which animal pharmacology suggests a disease-modifying action in rheumatoid arthritis (RA). "
2.	Inflammation (Inflammations) 03/01/1990 - "In a 5-day adjuvant arthritis model, romazarit inhibited the development of hindpaw inflammation with a minimum effective dose of 30 mg kg-1. " 03/01/1990 - "Romazarit showed little or no activity in models of acute inflammation such as rabbit skin edema, carrageenan pleurisy or UV-induced erythema. " 02/01/1991 - "In contrast to NSAIDs, romazarit was inactive in animal models of acute inflammation, and furthermore it did not inhibit the cyclooxygenase enzyme in vitro or in vivo. "
3.	Pleurisy (Pleuritis) 03/01/1990 - "Romazarit showed little or no activity in models of acute inflammation such as rabbit skin edema, carrageenan pleurisy or UV-induced erythema. "
4.	Erythema 03/01/1990 - "Romazarit showed little or no activity in models of acute inflammation such as rabbit skin edema, carrageenan pleurisy or UV-induced erythema. "
5.	Edema (Dropsy) 03/01/1990 - "Romazarit showed little or no activity in models of acute inflammation such as rabbit skin edema, carrageenan pleurisy or UV-induced erythema. "

Related Drugs and Biologics

1.	Collagenases (Collagenase)
2.	Dinoprostone (PGE2)
3.	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)
4.	Enzymes
5.	Carrageenan
6.	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)